Results 31 to 40 of about 833 (294)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Lesiones oculares predictoras de conteo de linfocitos CD4 < 200 cel/ml en pacientes infectados por VIH [PDF]

, 2019
El objetivo del estudio fue determinar lesiones oculares predictoras de conteo de linfocitos CD4 < 200 cél/ml en pacientes infectados por el virus de inmunodeficiencia humana (VIH).
Adrianzén, Rosa, García, Angélica
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

MANIFESTACIONES OCULARES DE LA ROSACEA EN PACIENTES RESIDENTES EN ALTURA [PDF]

, 2020
La rosácea es una enfermedad crónica inflamatoria que suele estar limitada a la cara. Se puede asociar a lesiones oculares..
Mendoza Salcedo, Nélida Silvia
core  

Cuidados de enfermería para la prevención y control de las lesiones oculares superficiales perioperatorias y en el paciente crítico. Revisión sistemática. [PDF]

, 2022
Las intervenciones del cuidado de los ojos en UCI y quirófano se pueden resumir en cuatro categorías principales: prevención del ojo seco, cierre del párpado, protocolos de higiene ocular y programas de cuidado de los ojos.
Guerra Juan, Adriana
core  

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Primer registro de anomalía ocular en Carollia perspicillata (Chiroptera: Phyllostomidae) en la República de Panamá

Actualidades Biológicas, 2023
Las anomalías oculares causadas debido a lesiones, enfermedades o mutaciones genéticas generan la pérdida total o parcial de la visión, lo cual afecta el desarrollo y comportamiento normal de los individuos afectados en su entorno natural. En murciélagos,
Nelson Guevara-Alvarado, Yulissa Díaz-Hernández   +1 more
doaj   +1 more source

Orbito-ocular lesions in Lagos

Nigerian Postgraduate Medical Journal, 2008
we present a 10year retrospective clinicopathologic study of 135 cases of orbito-ocular lesions. The aim is to document pattern of orbito-ocular lesions, with their site, age and sex distribution.The materials consisted of slides, paraffin embedded tissue blocks and histology request forms of all orbito-ocular samples received at the Morbid Anatomy ...
C C, Anunobi, F B, Akinsola, F B, Abdulkareem, O T, Aribaba, M A, Nnoli, A A F, Banjo   +5 more
openaire   +2 more sources

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Nocturnal Intraocular Pressure Monitoring With a Soft Contact Lens Sensor for Glaucoma Management

Advanced Materials, EarlyView.
A soft contact lens sensor enables continuous, noninvasive monitoring of nocturnal intraocular pressure (IOP) under closed‐eye sleep conditions. By integrating a highly compliant inductive–capacitive circuit onto a commercial lens, the device achieves record sensitivity and stable performance.
Yumin Dai, Tristan Michael Long, Oluwabunmi T. Oladele, Youngoh Lee, Feiyang Li, Ziheng Wang, Yeonji Oh, Junsang Lee, Taewoong Park, Tianhao Yu, Seokkyoon Hong, Kyeonghee Lim, Jinheon Jeong, Dawn Meyer Schneider, Hyerim Ra, Bryan W. Boudouris, Gillian C. Shaw, Shin Ae Park, Pete S. Kollbaum, Chi Hwan Lee   +19 more
wiley   +1 more source