Results 121 to 130 of about 107,994 (295)

El bien jurídico protegido en los delitos de lesiones [PDF]

, 2019
The purpose of this paper is to analyze the protected legal interest in the crimes of injury. Delimiting and studying each of the dogmatic options that jurisprudence and doctrine have advocated about what is the legal good protected in the crime of ...
García Maestre, Joel
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Estudio del tratamiento de lesiones vasculares mediante láser KTP y/o NEODIMIO [PDF]

Antecedentes: En dermatología, un gran número de patologías son tratadas con láser, entre ellas las patologías vasculares. Para ello generalmente se emplea el láser de colorante pulsado (PDL), así como el láser Nd: YAG y el láser KTP.
Masiá Plá, María
core   +1 more source

Lesiones vasculares abdominales: El desafío del cirujano de trauma Abdominal vascular lesions: The trauma surgeon's challenge

Revista Colombiana de Cirugía, 2007
Introducción: Las lesiones vasculares abdominales presentan los mayores índices de mortalidad y morbilidad entre todas las lesiones que puede sufrir una persona con trauma severo.
Juan A Asensio, Patrizio Petrone, Brian Kimbrell, Eric Kuncir   +3 more
doaj  

Lesões vasculares orais: avaliações clínicas, diagnósticas e terapêuticas [PDF]

, 2018
Introduction: Vascular disorders affect the head and neck regions with high incidence. When they affect the oral region, there is a predilection for lips, tongue and mouth commissure, predominantly in the female.
Vasconcelos, Marcelo Gadelha, Melo, Ana Karoline Vieira, Rodrigo, Rodrigo Gadelha, Morais Neves, Lucas Emmanuell   +3 more
core  

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

ANOMALÍAS VASCULARES DE PARTES BLANDAS: IMÁGENES DIAGNOSTICAS

Revista Chilena de Radiología, 2007
Las anomalías vasculares han sido tradicionalmente tratadas en conjunto aun cuando engloban patologías tan diferentes como hemangiomas y malformaciones vasculares.
José D Arce V, Cristian García B, Johanna Otero 0, Eduardo Villanueva A   +3 more
doaj  

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source