Results 121 to 130 of about 1,752 (296)

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Lesiones vasculares abdominales: El desafío del cirujano de trauma Abdominal vascular lesions: The trauma surgeon's challenge

Revista Colombiana de Cirugía, 2007
Introducción: Las lesiones vasculares abdominales presentan los mayores índices de mortalidad y morbilidad entre todas las lesiones que puede sufrir una persona con trauma severo.
Juan A Asensio, Patrizio Petrone, Brian Kimbrell, Eric Kuncir   +3 more
doaj  

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

ANOMALÍAS VASCULARES DE PARTES BLANDAS: IMÁGENES DIAGNOSTICAS

Revista Chilena de Radiología, 2007
Las anomalías vasculares han sido tradicionalmente tratadas en conjunto aun cuando engloban patologías tan diferentes como hemangiomas y malformaciones vasculares.
José D Arce V, Cristian García B, Johanna Otero 0, Eduardo Villanueva A   +3 more
doaj  

Lesiones vasculares asociadas en pacientes adultos con fractura de vértebra cervical visualizadas por angiotac en la UMAE HTyO Puebla

"Las lesiones cervicovasculares abarcan los traumatismos penetrantes o contusos en arterias carótidas y vertebrales, tanto en segmentos extra como intracraneales, ocasionados por flexión, extensión, rotación del cuello o golpes directos.
Provisor Martínez, Silvia Madelen
core  

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Caracterización clínica de las malformaciones vasculares cutáneas

A descriptive ambispective cross-sectional study was carried out to determine the clinical characterization of cutaneous vascular malformations (VM) in 82 patients who attended the consultation of the Dermatology Service of the Hospital Central ...
Moukhallalele, Karim, Nunes, Maria
core   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Estudios de imagen en el diagnóstico de los hemangiomas y malformaciones vasculares

Anales del Sistema Sanitario de Navarra, 2008
El diagnóstico de los hemangiomas y malformaciones vasculares cutáneas se basa en la historia clínica y la exploración física. Los estudios de imagen pueden ser necesarios para esclarecer y confirmar el diagnóstico, y para analizar la extensión de las ...
A. Martínez de la Cuesta
doaj