Results 161 to 170 of about 1,752 (296)

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

Laser therapy as a care technology in primary health care. [PDF]

Rev Esc Enferm USP
Povrezan GP, Bernardes LM, Souza EC, Soares RAQ, Oliveira E.   +4 more
europepmc   +1 more source

Geotrichosis: fungemia in a patient with acute lymphoblastic leukemia [PDF]

Biomedica, 2023
Álvarez-Rodríguez JC, Blanco-Bustos MP, Cuervo-Maldonado SI, Gómez-Rincón JC, Reyes Á.   +4 more
europepmc   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

[Imaging findings of adrenal gland lipoma: analysis and diagnosis]. [PDF]

Aten Primaria
García Rojas E, Aguilar Mérito PG, Reyes Gabriel D.   +2 more
europepmc   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

[Spontaneous splenic rupture. Case report and literature review]. [PDF]

Rev Med Inst Mex Seguro Soc, 2023
Reyes-Jaimes L, Camacho-Aguilera JF.
europepmc   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

[Design and evaluation of an oral health booklet during pregnancy]. [PDF]

Aten Primaria
Alcaraz-Orcajada M, Sanchez-Guerrero E, Serna-Muñoz C, Perez-Silva A, Ortiz-Ruiz AJ, Martínez-Beneyto Y.   +5 more
europepmc   +1 more source

[Use of Hemospray^® in Upper Gastrointestinal Bleeding due to Gastric Ischemia]. [PDF]

Acta Gastroenterol Latinoam, 2023
Mahler MA, Malvar FS, Pérez TM, Pizzala JE, Durán S, Mancini MDP, Giménez F, Manazzoni D, Abecia VH, Marcolongo M.   +9 more
europepmc   +1 more source