In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
How to Increase Children's and Adults' Interest in Learning From Disagreement. [PDF]
Blakey KH, Ronfard S.
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Comparative effects of orthokeratology and defocus incorporated multiple segment lenses on axial length elongation in children with bilateral myopic anisometropia. [PDF]
Jiang L +7 more
europepmc +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Demographic processes constrain global growth in gender egalitarianism. [PDF]
Akaliyski P +3 more
europepmc +1 more source
Differentiating Social and Moral Norms in Perceived Internalization. [PDF]
Deutchman P, Yang FY.
europepmc +1 more source
Effect of social support and social network on the risk of hearing aids abandonment among older adults with hearing loss. [PDF]
Fuentes-López E +4 more
europepmc +1 more source
Changing educational attainment as a driver of cohort changes in healthy longevity: a decomposition analysis of US birth cohorts. [PDF]
Shen T, van Raalte A, Payne CF.
europepmc +1 more source

