Results 231 to 240 of about 8,072,886 (297)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Less Is More: Optimized pharmacotherapy with improved coNtinuity of CarE in hospitaLized oLder peOple (LIMONCELLO): study protocol of a cluster randomized controlled trial. [PDF]

open access: yesBMC Geriatr
Cooijmans S   +38 more
europepmc   +1 more source

PENG block in elderly patients with hip fracture: less is more? A prospective observational monocentric study. [PDF]

open access: yesJ Anesth Analg Crit Care
Donatiello V   +11 more
europepmc   +1 more source

When less is more: sketching with minimizers in genomics. [PDF]

open access: yesGenome Biol
Ndiaye M   +8 more
europepmc   +1 more source

Adjuvant Chemotherapy in Colon Cancer: Simple is Better… Less is More. [PDF]

open access: yesSouth Asian J Cancer
Narayanan P   +19 more
europepmc   +1 more source

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