Results 71 to 80 of about 41,747 (330)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

ЛИЗИНГ ЖИЛОЙ НЕДВИЖИМОСТИ В РОССИИ: ТЕНДЕНЦИИ И ПЕРСПЕКТИВЫ

open access: yesCifra: Право
В данной статье рассматриваются правовые основы лизинга жилой недвижимости в Российской Федерации, анализируются тенденции и перспективы лизинговой деятельности с жилыми помещениями в России, а также рассматривается опыт иностранных государств в правовой
Залозная М.В.   +1 more
doaj   +1 more source

Analysis of leasing efficiency for the lessor

open access: yesIOP Conference Series: Materials Science and Engineering, 2020
Abstract The article analyzes the conditions under which the economic activity of a leasing company as a necessary link between manufacturers of modern machine-building equipment and machine-building enterprises is cost-effective. Because the lessor can simultaneously act as the lessee or purchaser of equipment from a manufacturer on the
openaire   +1 more source

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu   +16 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

New concepts of accounting of the rent relations: FSBU 25/2018 «Rent accounting»

open access: yesПутеводитель предпринимателя, 2020
In the conditions of integration of national standards of accounting into International Financial Reporting Standards objective need of reforming of the Russian rules of conducting accounting appears.
H. Sh. Nourmouhamedova, V. V. Bykova
doaj  

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

ANALYSIS OF CONCEPTUAL AND TECHNICAL (IN)CONSISTENCIES IN THE IFRS 16 “LEASES” ACCOUNTING MODEL [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2017
The purpose of this research is to identify a set of viable arguments for a critical analysis of the new standard in terms of the needs of users of financial statements, but also to clarify a number of conceptual and technical issues that we will have to
Ștefan Bunea
doaj  

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