Results 251 to 260 of about 316,536 (262)

Exploiting synthetic lethality to improve cancer therapy

Nature Reviews Clinical Oncology, 2017
Rene Bernards
exaly  

PARP inhibitors: Synthetic lethality in the clinic

Science, 2017
Christopher J Lord, Alan Ashworth
exaly  

Applying Synthetic Lethality for the Selective Targeting of Cancer

New England Journal of Medicine, 2014
Donal McLornan
exaly  

Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality

Cancer Cell, 2019
Jo Ishizawa, Ondrej Halgas, Ran Zhao
exaly  

Metabolic state matters for antibiotic lethality

Nature Reviews Microbiology, 2019
exaly  

Extensive Vasculogenesis, Angiogenesis, and Organogenesis Precede Lethality in Mice Lacking All αv Integrins

Cell, 1998
Richard O Hynes
exaly  

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

Cancer Cell, 2002
Allen Eng Juh Yeoh
exaly  

LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL

Cancer Cell, 2019
Salma Parvin, Elena M Cortizas, Isidro Sanchez-Garcia   +2 more
exaly  

Synthetic lethality screens point the way to new cancer drug targets

Nature Reviews Drug Discovery, 2017
exaly  

ROS enables aminoglycoside entry but not lethality

Nature Reviews Microbiology, 2013
exaly