Results 251 to 260 of about 202,850 (314)

Reprogramming the Immune Landscape of Inflammatory Breast Cancer

Advanced Science, EarlyView.
Inflammatory breast cancer is the most lethal subtype of breast cancer and is characterized by an immunosuppressive tumor microenvironment (TME) driven by a complex network of immune cells and inflammatory cytokines, contributing to its aggressiveness and treatment challenges. Immune checkpoint inhibitors, either alone or in combination, show potential
Verena Martinez‐Rodriguez, Suguru Ogata, Xiaoping Wang, Naoto T. Ueno   +3 more
wiley   +1 more source

RNA Interference Targeting <i>MaCht-2</i> Induces Severe Molting Defects and Lethality in <i>Monochamus alternatus</i>. [PDF]

Insects
Fang S, Chang X, Chen H, Shi J.
europepmc   +1 more source

Bi-allelic variants in NRDC cause a neurodevelopmental disorder characterized by neonatal lethality, microcephaly, and brain abnormalities. [PDF]

Am J Hum Genet
Pehlivan D, Sandoval A, Maroofian R, Lecoquierre F, Al Shamsi AM, Lee GS, Yesilbas O, Taylor P, McDougal MB, Bahrambeigi V, Aryani O, Ramirez JF, Salih KH, Al Alam C, Morsy H, Hussien H, Omar T, Abdelrazek IM, Brehin AC, Marafi D, Kalayci T, Rahma JA, Talbeya JK, Dabbah H, Verspyck E, Moosavian T, Fatih JM, Mitani T, Akay G, Calame DG, Guerrot AM, Chung WK, Houlden H, Lupski JR, Shalata A, Yoon WH.   +35 more
europepmc   +1 more source

<i>Caenorhabditis elegans</i> fed native gut microbiota have altered bioenergetic pathway utilization impacting mitochondrial function and susceptibility to pollutants.

Environ Sci Process Impacts
Bergemann CM, Jameson LE, Kenny-Ganzert IW, Huayta J, Castellano-Escuder P, Sarkar A, Ilkayeva OR, Sherwood DR, Hirschey MD, Meyer JN.   +9 more
europepmc   +1 more source

Essential Role of LapD in the Absence of Cardiolipins. [PDF]

Int J Mol Sci
Raina S, Maniyeri A, Ayyolath A, Klein G.   +3 more
europepmc   +1 more source

LUBAC PUB domain interactions restrict Met1-linked ubiquitination to prevent embryonic lethality and immune pathology

Gyrd-Hansen M, Rizk J, Timmermann F, Lyu W, Lee K, Kjær M, Beichler M, Fiil B, Jessen M, Franciosa G, Olsen J, Sauerland M, Damgaard R, Priesmann D.   +13 more
europepmc   +1 more source

From Germline Susceptibility to Therapeutic Vulnerability: DNA Damage Response Gene Mutations Driving Multiple Myeloma Evolution and Precision Therapy. [PDF]

Hum Mutat
Shen Q, Wang Y, Cai L, Qian J.
europepmc   +1 more source

Fundamentals and emerging frontiers in p53-targeted drug development. [PDF]

Biochem Biophys Rep
Long HD, Zhang N, Wang WE, Ma YS, Liu FX, Chen ZY, Lu CN, Wang XF, Han N, Cai YF, Yang C, Tang XM, Yu H, Jiang H, Fu D, Chu KJ, Wu WG.   +16 more
europepmc   +1 more source

THE LETHAL, POTENTIALLY LETHAL LESION MODEL

, 1983
openaire   +1 more source