Results 31 to 40 of about 4,467,404 (287)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The effectiveness of oximes against organophosphate poisoning [PDF]
MATEC Web of ConferencesOrganophosphate compounds (OPs) have been used by human in many ways over years. However, the misuse of organophosphate has been very common because their notorious toxicity.
Liu Qiming
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Understanding Indirect Request in Persian Language: Salience and Context Effects [PDF]
Journal of Language Horizons, 2019 This study is going to consider the factors vital for comprehension. The Graded Salience Hypothesis is the framework for this study. Persian indirect requests will be tested and the relation between different contexts, familiarity level and reading times
Leila Erfaniyan Qonsuli, Shahla Sharifi
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Some new trajectory patterns and periodic behaviors of unstable second-order digital filter with two’s complement arithmetic [PDF]
This letter shows some counter-intuitive simulation results that for some filter parameters in the extended boundaries of the stability triangle, the state vector will converge to a periodic orbit after some iterations, no matter what the initial ...
Wing-Kuen Ling, Kwong-Shum Tam, Yu X.
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
First molecular detection of Brachyspira suanatina on pig farms in Poland
Journal of Veterinary Research, 2023 Prior to the 2000s, swine dysentery was considered to be caused only by Brachyspira hyodysenteriae with contributing commensal intestinal anaerobes.
Cybulski Piotr +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Global Energy Interconnection, 2022 Coal-fired electricity enterprises are caught in the dilemma of relative fixed prices and rising costs under the scenario of decarbonization. Meanwhile, soaring market-oriented coal pricing results in coal enterprises’ increasing defaults on thermal coal
Yalin Chena +3 more
doaj +1 more source