Results 51 to 60 of about 13,833 (218)
En el individuo existe factores biopsicosocial o dimensiones como el contexto escolar, familiar y anímico los cuales cambian de manera radical a causa de una enfermedad crónica como la leucemia, desencadenando daños colaterales en la familia y en el ...
Diana Carolina Pimiento Idiarte +3 more
doaj +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Quality of Life and Needs of Patients Undergoing CAR‐T Cell Therapy: The Patients’ Perspective
Background Despite the strong emphasis in recent scientific literature on the pharmacological features of CAR‐T cells, patients’ quality of life (QoL) and needs, by contrast, have received little attention. Aim This study aims to investigate patients’ perspectives on their QoL and needs in a referral centre for CAR‐T cell treatment in Italy.
S. Alfieri +10 more
wiley +1 more source
Aplicações da metodologia fish em citogenética de neoplasias. [PDF]
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.As neoplasias surgem em conseqüência de mutações acumulativas no material genético (DNA) de células normais, as quais sofrem alterações progressivas até se ...
Foppa, Carolina Ester
core
Abstract Background Clinical trials (CTs) are essential for expanding treatment options across hematologic malignancies (HM) and providing access to novel treatments. However, older adults with HM are often underrepresented in CTs, and a national‐level evaluation of factors influencing their participation is lacking.
Inna Y. Gong +8 more
wiley +1 more source
ABSTRACT Nodal follicular helper T‐cell (T FH) lymphoma of the angioimmunoblastic (AITL) subtype has a dismal prognosis. Using whole‐exome sequencing (n = 124), transcriptomic (n = 78), and methylation (n = 40) analysis, we identified recurrent mutations in known epigenetic drivers (TET2, DNMT3A, IDH2 R172 ) and novel ones (TET3, KMT2D).
Alyssa Bouska +43 more
wiley +1 more source
Abstract Objectives Paediatric acute liver failure (PALF) is a rare but life‐threatening condition, yet comprehensive epidemiological data in Germany are lacking. Our study aimed to systematically analyse incidence, aetiology, and outcome of PALF in Germany.
Dominic Lenz +40 more
wiley +1 more source
La leucemia cutis resulta de la infiltración de la epidermis, la dermis, y/o la grasa subcutánea por leucocitos neoplásicos o sus precursores, y puede tener diferentes apariencias y presentaciones, muchas de las cuales son similares a aquellas de los linfomas cutáneos.
Claudia Vélez Campuzano +3 more
openaire +1 more source
El cáncer incide en el niño y en su entorno familiar y social de forma devastadora. Posiblemente ninguna experiencia vital tiene tal capacidad para alterar la vida del núcleo familiar. La leucemia es una enfermedad crónica que afecta a los niños y a
Nancy Arcos Proaño
doaj +1 more source
Prospective evaluation of 92 protein biomarkers for early detection of endometrial cancer
What's new? In this prospective study, the authors evaluated the discrimination capacity of 92 cancer‐related proteins as potential early detection biomarkers for endometrial cancer using blood samples from two large‐scale European population cohorts (EPIC and Janus).
Victoria Cooley +12 more
wiley +1 more source

