Results 21 to 30 of about 76,777 (216)
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source
Effect of Cobra Venom on Leucocytes
Intermittent injections of sublethal doses of the venom of Naja haje of Egypt caused temporary leucopenia followed by leucocytosis in guinea-pigs and rabbits. There was always a rise in the percentage of neutrophil leucocytes and a corresponding drop in
Fouad Khalil +2 more
core +1 more source
ABSTRACT Background Chronic limb‐threatening ischemia (CLTI) is a severe form of lower‐extremity artery disease characterized by distal lesions and microcirculatory impairment, limiting revascularization efficacy. Rheocarna is a direct hemoperfusion low‐density lipoprotein (LDL) adsorption device with potential rheological and anti‐inflammatory ...
Kunihiro Ishioka +12 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
MULTIPLE ROLE OF LEUCOCYTES IN CORONARY HEART DISEASE
A summary provided, on the role of leucocytes as an independent risk factor for coronary heart disease (CHD). Various aspects analyzed, of the leucocytes role in atherosclerosis and CHD development.
А. V. Panov +3 more
core +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Leucocytes tethered in the posterior esophageal lumen.
(A) Confocal image of adult male S. mansoni stained with Langeron's carmine, showing a string of host leucocytes (LE) tethered in the lumen (L), surrounded by extracellular material (arrowed).
Gillian M. Vance (437293) +7 more
core +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Lumpsucker kidney used for isolation of leucocytes.
Dissected kidney where the section used for isolation of leucocytes from the left cranial lobe is marked.
Kristian Ulven (301905) +5 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source

