Results 191 to 200 of about 41,795 (272)

Pharmacogenomics of Thiopurine Drugs: A Bench‐To‐Bedside Success Story in Thailand

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Thiopurine drugs are the cornerstone treatment for many diseases such as acute lymphoblastic leukemia (ALL), organ rejection, inflammatory bowel disease (IBD), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and other autoimmune diseases.
Mohitosh Biswas   +3 more
wiley   +1 more source

Genetic Determinants of Hematopoietic Toxicity Risk in Thai Pediatric Patients Undergoing 6‐Mercaptopurine Treatment

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The nucleoside diphosphate‐linked moiety X‐type motif 15 (NUDT15) has been identified as a key genetic determinant of 6‐mercaptopurine (6‐MP)‐induced hematopoietic toxicity in populations with a high frequency of NUDT15 variants but a low frequency of thiopurine S‐methyltransferase (TPMT) variants.
Kanyarat Khaeso   +8 more
wiley   +1 more source

White Blood Cell Enumeration and Differential by Flow Cytometry: The ICSH WBC Reference Method

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 1, Page 93-101, February 2026.
ABSTRACT Introduction The current reference method for the white blood cell (WBC) differential is manual smear review as outlined in CLSI H20‐A2. As with many manual methods, it suffers from a number of challenges including dependence upon the expertise of the interpreter, the quality of the smear and stain, when dysplastic features make cell ...
Benjamin D. Hedley   +6 more
wiley   +1 more source

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