Results 261 to 270 of about 253,634 (313)

Clonal haematopoiesis in chronic lymphocytic leukaemia: Biology, inflammaging and clinical implications in the era of targeted therapy. [PDF]

Clin Transl Med
Martino EA, Caserta S, Skafi M, Alvaro ME, Bruzzese A, Amodio N, Lucia E, Olivito V, Labanca C, Mendicino F, Vigna E, Morabito F, Gentile M.   +12 more
europepmc   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Adult Acute Myeloid Leukaemia With <i>DDX3X::MLLT10</i>: A Rare Entity With Significant Unmet Clinical Needs. [PDF]

EJHaem
Ng JY, Sr A, Joshi M, Talaulikar D.
europepmc   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

Chronic myeloid leukaemia: have basophils gone the way of the Dodo bird? [PDF]

Leukemia
Turcsanyi L, Zhang XS, Kudelka M, Kubikova K, Radvansky M, Yang S, Kriegova E, Juranova J, Mayer J, Klamova H, Belohlavkova P, Karas M, Stejskal L, Cmunt E, Othus M, Gale RP, Jiang Q, Faber E.   +17 more
europepmc   +1 more source

DE-ESCALATION OF TYROSINE KINASE INHIBITOR THERAPY IS SAFE IN CHRONIC MYELOID LEUKAEMIA IN DURABLE MOLECULAR RESPONSE (>= MR3 FOR >= 12 MONTHS): INITIAL RESULTS IN THE BRITISH DESTINY STUDY [PDF]

, 2016
Apperley, J, Clark, R, Coffey, T, Copland, M, Foroni, L, O'Brien, S, Pocock, C, Polydoros, F, Salim, R, Smith, G   +9 more
core  

Impact of an Anti-infection Double Lumen Bundle on the incidence of central venous catheter-related infections in haematological patients: a retrospective cohort study. [PDF]

Infect Prev Pract
Lazarevic Lindblad M, Pålsson E, Lazarevic V, Borgquist O, Kander T.   +4 more
europepmc   +1 more source

A study of clinical profile and outcomes of paediatric patients with acute myeloid leukaemia. [PDF]

Ecancermedicalscience
Barbhuiyan S, Hazarika M, Iqbal A, Kakunje M, Raval HP, Sarma A, Deka R.   +6 more
europepmc   +1 more source

Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia

Blood Cancer Journal
Rishi S. Kotecha, Sarah M. Trinder, Anastasia M. Hughes, Benjamin H. Mullin, Sarah Rashid, Jinbo Yuan, Jiake Xu, Owen Duncan, Patrycja Skut, Grace-Alyssa Chua, Sajla Singh, Joyce Oommen, Richard B. Lock, Ursula R. Kees, Sebastien Malinge, Vincent Kuek, Laurence C. Cheung   +16 more
doaj   +1 more source

Primary Cutaneous Adult T-cell Leukaemia/Lymphoma Presenting as Generalized Purpura.

Acta Derm Venereol
Watanabe K, Natsuga K, Onozawa M, Kikuchi T, Ujiie H.   +4 more
europepmc   +1 more source