Results 1 to 10 of about 37,215 (232)

Population preference values for treatment outcomes in chronic lymphocytic leukaemia: a cross-sectional utility study [PDF]

Health and Quality of Life Outcomes, 2010
Given that treatments for chronic lymphocytic leukaemia (CLL) are palliative rather than curative, evaluating the patient-perceived impacts of therapy is critical. To date, no utility (preference) studies from the general public or patient perspective have been conducted in CLL.
Meiklejohn David, Leach Michael, Davies John, Beusterien Kathleen M, Grinspan Jessica L, O'Toole Alison, Bramham-Jones Steve   +6 more
openaire   +3 more sources

Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Nature Communications, 2021
Genome wide association studies in cancer are used to understand the heritable genetic contribution to disease risk. Here, the authors perform a genome wide association study in European patients with acute myeloid leukemia and identify loci associated ...
Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, Jude Fitzgibbon, Richard A. Larson, Michelle M. Le Beau, Wendy Stock, Olaf Heidenreich, Abrar Alharbi, David J. Allsup, Richard S. Houlston, Jean Norden, Anne M. Dickinson, Elisabeth Douglas, Clare Lendrem, Ann K. Daly, Louise Palm, Kim Piechocki, Sally Jeffries, Martin Bornhäuser, Christoph Röllig, Heidi Altmann, Leo Ruhnke, Desiree Kunadt, Lisa Wagenführ, Heather J. Cordell, Rebecca Darlay, Mette K. Andersen, Maria C. Fontana, Giovanni Martinelli, Giovani Marconi, Miguel A. Sanz, José Cervera, Inés Gómez-Seguí, Thomas Cluzeau, Chimène Moreilhon, Sophie Raynaud, Heinz Sill, Maria Teresa Voso, Francesco Lo-Coco, Hervé Dombret, Meyling Cheok, Claude Preudhomme, Rosemary E. Gale, David Linch, Julia Gaal-Wesinger, Andras Masszi, Daniel Nowak, Wolf-Karsten Hofmann, Amanda Gilkes, Kimmo Porkka, Jelena D. Milosevic Feenstra, Robert Kralovics, David Grimwade, Manja Meggendorfer, Torsten Haferlach, Szilvia Krizsán, Csaba Bödör, Friedrich Stölzel, Kenan Onel, James M. Allan   +82 more
doaj   +1 more source

Direct and indirect costs of families with a child with acute lymphoblastic leukaemia in an academic hospital in China: a cross-sectional survey [PDF]

BMJ Open, 2019
Objectives To estimate the direct and indirect costs in families with a child with acute lymphoblastic leukaemia (ALL) in China. Design A single-site, cross-sectional survey of primary caregiver of a child with ALL was performed.
Xin Li, Yijiong Ren
openaire   +3 more sources

A new monoclonal antibody detects downregulation of protein tyrosine phosphatase receptor type γ in chronic myeloid leukemia patients

Journal of Hematology & Oncology, 2017
Background Protein tyrosine phosphatase receptor gamma (PTPRG) is a ubiquitously expressed member of the protein tyrosine phosphatase family known to act as a tumor suppressor gene in many different neoplasms with mechanisms of inactivation including ...
Marzia Vezzalini, Andrea Mafficini, Luisa Tomasello, Erika Lorenzetto, Elisabetta Moratti, Zeno Fiorini, Tessa L. Holyoake, Francesca Pellicano, Mauro Krampera, Cristina Tecchio, Mohamed Yassin, Nader Al-Dewik, Mohamed A. Ismail, Ali Al Sayab, Maria Monne, Claudio Sorio   +15 more
doaj   +1 more source

The Diagnosis of Feline Leukaemia Virus (FeLV) Infection in Owned and Group-Housed Rescue Cats in Australia

Viruses, 2019
A field study was undertaken to (i) measure the prevalence of feline leukaemia virus (FeLV) exposure and FeLV infection in a cross-section of healthy Australian pet cats; and (ii) investigate the outcomes following natural FeLV exposure in two Australian
Mark Westman, Jacqueline Norris, Richard Malik, Regina Hofmann-Lehmann, Andrea Harvey, Alicia McLuckie, Martine Perkins, Donna Schofield, Alan Marcus, Mike McDonald, Michael Ward, Evelyn Hall, Paul Sheehy, Margaret Hosie   +13 more
doaj   +1 more source

Unmet supportive care needs and its relation to quality of life among adult acute leukaemia patients in China: a cross-sectional study [PDF]

Health and Quality of Life Outcomes, 2020
Abstract Background: Patients with acute leukaemia (AL) usually require prolonged periods of hospitalisation. The treatment and clinical symptoms may lead to patients’ supportive care needs (SCNs) not being met and impairs their quality of life (QoL). Studies on QoL and SCNs among AL patients are limited.
Jie Yan, Ying Wang, Jingyi Chen, Chunfeng Wang, Yingchun Lin, Rong Hu, Yong Wu   +6 more
openaire   +3 more sources

Impact of ELN recommendations in the management of first‐line treated chronic myeloid leukaemia patients: a French cross‐sectional study [PDF]

British Journal of Haematology, 2016
SummaryThe availability of tyrosine kinase inhibitors has extended therapeutic options for chronic myeloid leukaemia (CML) patients. Monitoring recommendations and clinical response goals have recently been updated. The objective of this study was to describe the profile of CML patients in chronic phase currently receiving first‐line therapy, including
Gabriel, Etienne, Francoise, Huguet, Agnès, Guerci-Bresler, Franck E, Nicolini, Frédéric, Maloisel, Valérie, Coiteux, Charles, Dauriac, Nathalie, Carpentier, Isabelle, Bourdeix, Michel, Tulliez, Pascale, Cony-Makhoul   +10 more
openaire   +2 more sources

Characterisation of cells markers associated with IKZF1plus in BCP-ALL

Translational Oncology
The presence of IKZF1 deletions has been associated with an increased relapse rate in B-cell precursor acute lymphoblastic leukaemia (BCP-ALL). There is a particular subset of IKZF1del cases called IKZF1plus (defined by the co-occurrence of IKZF1del and ...
Caroline Barbieri Blunck, Caroline Pires Poubel, Bruno A. Lopes, Thayana C. Barbosa, Ana Luiza Tardem Maciel, Elaine Sobral da Costa, Ariadne da Rocha Figueiredo, Marcelo G.P. Land, Márcia Trindade Schramm, Maura Rosane Valério Ikoma-Coltutato, Renan Garcia Gomes, Mecneide Mendes Lins, Thais Ferraz Aguiar, Marcela Braga Mansur, Mariana Emerenciano   +14 more
doaj   +1 more source

Body composition and bone health in long-term survivors of acute lymphoblastic leukaemia in childhood and adolescence: the protocol for a cross-sectional cohort study [PDF]

BMJ Open, 2015
Introduction Success in the treatment of young people with cancer, as measured conventionally by survival rates, is mitigated by late effects of therapy that impose a burden of morbidity and limit life expectancy.
Barr, Ronald, Nayiager, Trishana, Gordon, Christopher, Marriott, Christopher, Athale, Uma   +4 more
openaire   +2 more sources

Late pulmonary adverse effects in childhood and adolescent acute lymphoblastic leukaemia survivors: a cross-sectional ALL-STAR Lungs study [PDF]

ERJ Open Research
Background Childhood acute lymphoblastic leukaemia (ALL) survival rates have improved, reaching 95%. However, 25–50% of survivors experience significant treatment-related toxicities. This study investigated late pulmonary adverse effects, including pulmonary symptoms and pulmonary function, in childhood ALL ...
Sonja Izquierdo Riis Meyer, Mette Tiedemann Skipper, Birgitte Klug Albertsen, Ruta Tuckuviene, Peder Skov Wehner, Thomas Leth Frandsen, Kjeld Schmiegelow, Liv Andrés-Jensen, Kim Gjerum Nielsen, Sune Leisgaard Mørck Rubak   +9 more
openaire   +6 more sources