Results 121 to 130 of about 37,215 (232)

Parental, pregnancy and neonatal characteristics during the perinatal period as potential risk factors for childhood cancer: FeToxCancer case-control study. [PDF]

PLoS One
Stajnko A, Thacher JD, Oudin A, Lindh C, Lundh T, Øra I, Selander J, Rylander L, Albin M, Källén K, Broberg K.   +10 more
europepmc   +1 more source

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

BMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai, Rui Zhang, Haiyin Yang, Jiyue Xing, Tianyuan Hu, Mengxi Zhu, Rui Li, Xiaoli Chen, Beibei Zhao, Yang Lan, Stefan Barth, Yuanyu Huang, Li Zhang, Mengjie Zhang, Huining He   +14 more
wiley   +1 more source

Lymphoma, multiple myeloma and leukaemia incidence in regions of Belarus most heavily contaminated by the Chernobyl accident. [PDF]

Int J Cancer
Zupunski L, Yaumenenka A, Veyalkin I, Minenko V, Moiseyev P, Schüz J, Kukhta T, Trofimik S, Harbron R, Drozdovitch V, Ostroumova E.   +10 more
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Quality of life and symptoms in acute myeloid leukaemia with early palliative care: real-world observational study. [PDF]

BMJ Support Palliat Care
Potenza L, Giusti D, Borelli E, Colaci E, Morandi F, Cuoghi Costantini R, Del Giovane C, Forghieri F, Morselli M, Bettelli F, Pioli V, Cuoghi A, Bresciani P, Messerotti A, Gilioli A, Marasca R, Cassanelli L, Parisotto A, Cretì F, Mucciarini C, Bigi S, D'Amico R, Efficace F, Odejide O, Bruera E, Zimmermann C, Luppi M, Bandieri E.   +27 more
europepmc   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

Incidence of severe COVID-19 in patients with chronic lymphocytic leukaemia or indolent B-cell non-Hodgkin lymphoma who received vaccination and pre-exposure prophylaxis with tixagevimab and cilgavimab in Italy: An observational study by the GIMEMA working party on chronic lymphoproliferative disorders and by the Fondazione Italiana Linfomi. [PDF]

Br J Haematol
Rigolin GM, Soddu S, Dondolin R, Frustaci AM, Scortechini I, Mauro FR, Angotzi F, Motta M, Scarfò L, Mengarelli A, Giordano A, Martinelli S, Patti C, Sportoletti P, Sanna A, Maschio N, Riccioni R, Viganò CV, Tafuri A, Piciocchi A, Fazi P, Luminari S, Ferreri AJM, Gini G, Ghia P, Cuneo A.   +25 more
europepmc   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Prevalence of multiple morbidities and cancers in individuals with Down syndrome: A matched descriptive study using linked electronic health record data. [PDF]

PLoS One
McKenna C, Khanna KY, Cupp MA, Faijue DD, Schilder AGM, Gonzalez-Izquierdo A, Ul Arfeen MQ, Strydom A, Hargreaves D, Lee RXN, Lakhanpaul M, Manikam L.   +11 more
europepmc   +1 more source

Single‐Cell Profiling Reveals Distinct Immune Hallmarks in Untreated Primary Colorectal and Liver Metastasis Cancers

Chronic Diseases and Translational Medicine, EarlyView.
Features the major cell type compositions among colon and liver metastasis. (A) The study design for single‐cell data analysis. (B) The annotated major cell types. Each type was labeled with a special color. (C) Dot plot of canonical marker genes for major cell types. (D) Bar plot of the percentage for each cell type in individuals. (E) Bar plot of the
Zhixun Zhao, Haipeng Chen, Xu Guan, Zheng Jiang, Zheng Liu, Ming Yang, Hengchang Liu, Tianli Chen, Shuangmei Zou, Yibo Gao, Xishan Wang   +10 more
wiley   +1 more source