Results 11 to 20 of about 18,961 (179)

Frequent NPM1 mutation, monoblastic/monocytic origin and prognostic significance of organ and system involvement in myeloid sarcoma: a multicenter study [PDF]

The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract Myeloid sarcoma (MS) is a tumorous extramedullary proliferation of blast or blast equivalent cells (e.g., promonocytes or promyelocytes). The most frequent cutaneous presentation is often referred to as leukemia cutis (LC). These lesions, especially without the clinical context of a known bone marrow disease, pose a differential diagnostic ...
Alex Jenei, Béla Kajtár, Tamás László, Hazem A Juratli, Livia Vida, Ágota Szepesi, Réka Mózes, Botond Timár, Jörg Halter, Stefan Dirnhofer, Alexandar Tzankov   +10 more
wiley   +2 more sources

Analysis of Patients With Monocytic and Monocytic‐Like Acute Myeloid Leukemia, Including AML‐M4 and AML‐M5, Treated With Venetoclax Plus Azacitidine [PDF]

Am J Hematol
American Journal of Hematology, Volume 101, Issue 3, Page 577-580, March 2026.
Marina Konopleva, Courtney D. DiNardo, Yan Sun, Paul Jung, Sanam Loghavi, Jalaja Potluri, Monique Dail, Brenda Chyla, Daniel A. Pollyea   +8 more
wiley   +2 more sources

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis [PDF]

FEBS Open Bio
Acute myeloid leukemia (AML) is a bone marrow malignancy characterized by arrested early‐stage hematopoietic precursor development. Differentiation therapy, which induces terminal differentiation of immature leukemic cells, is less toxic than standard ...
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
doaj   +2 more sources

FEATURES OF A DIFFERENTIAL DIAGNOSIS OF PEDIATRIC ACUTE MONOCYTIC LEUKEMIA (AML-M5a) ON THE EXAMPLE OF A CLINICAL CASE

Южно-Российский онкологический журнал, 2020
The aim of this work was to assess the significance of investigating clinical and laboratory parameters for diagnosing acute monocytic leukemia in children on the basis of a clinical case. The article demonstrates specific features of differentiating AML
O. I. Kit, N. K. Guskova, O. N. Selyutina, V. V. Dmitrieva, I. A. Novikova, I. S. Torpujyan, V. R. Zakharchenko   +6 more
doaj   +1 more source

The First Reported Case of Allogenic Hematopoietic Stem Cell Transplantation for CML Blast Phase (Monocytic Lineage) in the Tyrosine Kinase Inhibitor Era

Case Reports in Oncology, 2022
Chronic myeloid leukemia (CML) blast phase (monocytic lineage) is extremely rare. A 39-year-old Japanese man was diagnosed with CML blast phase (monocytic lineage).
Shinya Yamada, Kotaro Arita, Yukio Kondo, Shuichi Mizuta, Hirokazu Okumura   +4 more
doaj   +1 more source

Differential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapy

Haematologica, 2015
High expression of the chemokine receptor 4, CXCR4, associated with a negative prognosis in acute myeloid leukemia, is related to hypoxia. Because CXCR4 expression is under the post-transcriptional control of microRNA-146a in normal and leukemic ...
Isabella Spinello, Maria Teresa Quaranta, Rosa Paolillo, Elvira Pelosi, Anna Maria Cerio, Ernestina Saulle, Francesco Lo Coco, Ugo Testa, Catherine Labbaye   +8 more
doaj   +1 more source

Acute Monocytic Leukemia Masquerading Behçet’s Disease-Like Illness at Onset in an Elderly Female

Case Reports in Hematology, 2016
A previously healthy 74-year-old Japanese female was hospitalized with fever and high C-reactive protein. She developed palatal herpangina-like aphthous ulcers, localized intestinal wall thickening, terminal ileum ulcers, and an erythematous acneiform ...
Shigeru Koba, Toshio Sekioka, Sorou Takeda, Aya Miyagawa-Hayashino, Keisuke Nishimura, Shinsaku Imashuku   +5 more
doaj   +1 more source

The prognosis biomarkers based on m6A-related lncRNAs for myeloid leukemia patients

Cancer Cell International, 2022
Background Chronic myeloid leukemia (CML) and acute myeloid leukemia (AML) are two common malignant disorders in leukemia. Although potent drugs are emerging, CML and AML may still relapse after the drug treatment is stopped. N6-methyladenosine (m6A) and
Li-Rong Yang, Zhu-Ying Lin, Qing-Gang Hao, Tian-Tian Li, Yun Zhu, Zhao-Wei Teng, Jun Zhang   +6 more
doaj   +1 more source

Bioinformatic prediction and functional characterization of human KIAA0100 gene

Journal of Pharmaceutical Analysis, 2017
Our previous study demonstrated that human KIAA0100 gene was a novel acute monocytic leukemia-associated antigen (MLAA) gene. But the functional characterization of human KIAA0100 gene has remained unknown to date. Here, firstly, bioinformatic prediction
He Cui, Xi Lan, Shemin Lu, Fujun Zhang, Wanggang Zhang   +4 more
doaj   +1 more source

JAK2-negative acute monocytic leukemia with TET2 mutation in essential thrombocythemia with JAK2 mutation with literature review

Leukemia Research Reports, 2020
Essential thrombocythemia (ET) is an indolent myeloproliferative neoplasm (MPN) with a transformation to acute myeloid leukemia in
Toshie Ogasawara, Kiyotaka Kawauchi, Takuya Ono, Shoko Marshall, Kotaro Shide, Kazuya Shimoda, Naoki Mori, Hiroshi Sakura   +7 more
doaj   +1 more source