Integrative Analysis of Genetic Risk Factors for Acute Myeloid Leukemia Using Mendelian Randomization and Single-Cell RNA Sequencing Validation. [PDF]
Xia T, Wen R, Wu G, Hong Y, Luo D.
europepmc +1 more source
Histiocytosis development and clinical variation through the lens of genomics
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps +3 more
wiley +1 more source
Donor-Related Factors Affecting Haploidentical HSCT Outcomes in Acute Leukemia: A Single-Center Retrospective Cohort Study of a Modified Combination of Anti-Thymocyte Globulin and Post-Transplant Cyclophosphamide. [PDF]
Mashayekhi M +11 more
europepmc +1 more source
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde +4 more
wiley +1 more source
A Reliable Method for Thawing Primary AML and CMML Mononuclear Cells to Preserve Viability and Function. [PDF]
Lim K +5 more
europepmc +1 more source
The <i>NFIA::CBFA2T3</i> identifies a molecularly defined subgroup of acute erythroid leukemia/erythroid sarcoma. [PDF]
Brunetti M +8 more
europepmc +1 more source
Hemophagocytosis in acute myeloid leukemia
Claudia Morales-Olvera +1 more
openaire +3 more sources
Dual-target CAR-T cell therapy: latest updates from the 2025 ASH annual meeting. [PDF]
Feng S, Kong R, Xiao L, Zhou X.
europepmc +1 more source
Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan +5 more
wiley +1 more source
Abnormal Eosinophils With Large, Distinctly Basophilic Granules (Harlequin Cells) on Peripheral Blood Smear: A Clue for Diagnosing Chronic Myeloid Leukemia. [PDF]
Cai J, Yue C, Tomassetti S.
europepmc +1 more source

