Results 241 to 250 of about 402,161 (308)

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu, Jin‐Hao Chen, Yan‐Fang Wang, Xiao Wu, Hui‐Yun Ni, Qiu‐Rong Zhang   +5 more
wiley   +1 more source

The Outcomes of Myeloid Sarcoma in 64 Pediatric Patients and the Impact of Allogeneic Hematopoietic Stem Cell Transplantation on Treatment Results. [PDF]

Children (Basel)
Samborska M, Skalska-Sadowska J, Wachowiak J, Czogała M, Balwierz W, Skoczeń S, Bartoszewicz N, Styczyński J, Ociepa T, Urasiński T, Wróbel G, Kałwak K, Muszyńska-Rosłan K, Szmydki-Baran A, Malinowska I, Łaguna P, Mizia-Malarz A, Tomaszewska R, Szczepański T, Chodała-Grzywacz A, Karolczyk G, Maciejka-Kembłowska L, Kozłowska M, Irga-Jaworska N, Mycko K, Badowska W, Bobeff K, Młynarski W, Chaber R, Zawitkowska J, Drabko K, Derwich K.   +31 more
europepmc   +1 more source

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

Targetoid ulcerating eruption in a previously healthy man. [PDF]

JAAD Case Rep
Giordano JA, Cohen OG, Flowers RH, Moore ME.   +3 more
europepmc   +1 more source

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song, Han‐Xu Jin, Yuan‐Xin Sun, Wen‐Hui Kou, Xiao‐Ning Niu, Huan‐Huan Wang, Ting‐Ting Zhong, Ping Gu   +7 more
wiley   +1 more source

Characterization of Acute Myeloid Leukemia With t(16;21) Translocation: Cytogenetic, Molecular, and Immunophenotypic Findings. [PDF]

World J Oncol
Bravo-Davila M, Espinoza-Rodrigez D, Orejon-Huarancca J, Zapata Dongo RJ.   +3 more
europepmc   +1 more source

A Rare Hybrid Presentation: Coexistence of Necrotizing and Histiocytoid Variants of Sweet Syndrome (SS) in a Patient With Acute Myeloid Leukemia (AML). [PDF]

Cureus
Al Rawahi A, Al-Qutaiti Z, Alfarsi M.
europepmc   +1 more source

Limited expression of B-cell maturation antigen in acute myeloid leukemia. [PDF]

J Immunother Cancer
Ran Y, Cheng W, Yi X, Yang S, Zhang W, Xu J.   +5 more
europepmc   +1 more source

Characterizing the impact of MLL fusion variants and fusion partners on leukemia plasticity using a human CRISPR-engineered MLL-rearranged leukemia model. [PDF]

Neoplasia
Radszuweit P, Fitzel R, Bruestl S, Hentrich T, Korkmaz F, Mankel B, González-Menéndez I, Rudat S, Marschalek R, Erkner E, Keppeler H, Schairer R, Luib L, Mezger M, Quintanilla-Martinez L, Schulze-Hentrich J, Lengerke C, Schneidawind D, Schneidawind C.   +18 more
europepmc   +1 more source

Case Report: A primary breast collision tumor composed of myeloid sarcoma and invasive ductal carcinoma. [PDF]

Front Oncol
Ding JS, Zhang M, Zhou F.
europepmc   +1 more source