Results 21 to 30 of about 1,123,126 (369)

The role of dwelling type when estimating the effect of magnetic fields on childhood leukemia in the California Power Line Study (CAPS). [PDF]

, 2020
PurposeThe type of dwelling where a child lives is an important factor when considering residential exposure to environmental agents. In this paper, we explore its role when estimating the potential effects of magnetic fields (MF) on leukemia using data ...
Amoon, AT, Arah, OA, Crespi, CM, Kheifets, L, Nguyen, A, Vergara, X, Zhao, X   +6 more
core  

A thoracic-epidural granulocytic sarcoma case that was diagnosed preceding the onset of and that recurred co-incidental to acute promyelocytic leukemia, which developed after surgical treatment. [PDF]

, 2004
Granulocytic sarcoma or chloroma is a tumor seen in myelocytic leukemia. Spinal epidural onset is rare and is generally seen before or together with the onset of myelocytic leukemia.
Bayraktaroglu, Taner, Borazan, Ali, Demircan, Nejat, Ozdemir, Huseyin, Ozer, Tulay, Savranlar, Ahmet, Ustundag, Yucel   +6 more
core   +1 more source

Phase 1 study of an anti-CD33 immunotoxin, humanized monoclonal antibody M195 conjugated to recombinant gelonin (HUM-195/rGEL), in patients with advanced myeloid malignancies

Haematologica, 2013
We conducted a phase 1 study of an anti-CD33 immunotoxin, humanized monoclonal antibody M195 conjugated to recombinant gelonin (HUM-195/rGEL), in patients with relapsed, refractory myeloid leukemias.
Gautam Borthakur, Michael G. Rosenblum, Moshe Talpaz, Naval Daver, Farhad Ravandi, Stefan Faderl, Emil J. Freireich, Tapan Kadia, Guillermo Garcia-Manero, Hagop Kantarjian, Jorge E. Cortes   +10 more
doaj   +1 more source

Association between Outdoor Air Pollution and Childhood Leukemia: A Systematic Review and Dose-Response Meta-Analysis. [PDF]

, 2019
BackgroundA causal link between outdoor air pollution and childhood leukemia has been proposed, but some older studies suffer from methodological drawbacks.
Abdul Rahman HI, Alessio Crippa, Andreoli R, Andrew S. Park, Elizabeth E. Hatch, IARC, IARC (International Agency for Research on Cancer), Julia E. Heck, Kenneth J. Rothman, Marco Vinceti, Nicola Orsini, Tommaso Filippini   +11 more
core   +1 more source

The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1-CD44 axis. [PDF]

, 2020
The endosteal bone marrow niche and vascular endothelial cells provide sanctuaries for leukemic cells. In murine chronic myeloid leukemia (CML) CD44 on leukemia cells and E-selectin on bone marrow endothelium are essential mediators for the engraftment ...
Aggoune, D., Godavarthy, P., Hayduk, N., Herkt, S., Krause, D., Kumar, R., Lausen, J., Lucas, T., Manavski, Y., Müller, M., Oehler, V., Oellerich, T., Pan, K., Pereira, R., Saussele, S., Voutsinas, J., Weissenberger, E., Wu, Q.   +17 more
core   +2 more sources

STAT3 mutation impacts biological and clinical features of T-LGL leukemia [PDF]

, 2017
STAT3 mutations have been described in 30-40% of T-large granular lymphocyte (T-LGL) leukemia patients, leading to STAT3 pathway activation. Considering the heterogeneity of the disease and the several immunophenotypes that LGL clone may express, the aim
BARILA', GREGORIO, BERNO, TAMARA, BOSCARO, ELISA, CABRELLE, ANNA, CALABRETTO, GIULIA, DE MARCH, ELENA, ERCOLIN, CHIARA, FACCO, MONICA, GATTAZZO, CRISTINA, Lamy, Thierry, LEONCIN, MATTEO, Moignet, Aline, PAGNIN, ELISA, Pastoret, C\ue9dric, PIAZZA, FRANCESCO, Roussel, Mikael, SEMENZATO, GIANPIETRO CARLO, Teolato, Sara, TERAMO, ANTONELLA, TRENTIN, LIVIO, ZAMBELLO, RENATO   +20 more
core   +1 more source

Residential mobility and childhood leukemia. [PDF]

, 2018
AimsStudies of environmental exposures and childhood leukemia studies do not usually account for residential mobility. Yet, in addition to being a potential risk factor, mobility can induce selection bias, confounding, or measurement error in such ...
A.T. Amoon, Alba, C.M. Crespi, Canfield, Champion, Charles, Chen, Clark, Clark, Crespi, Feychting, Goldberg, Green, Guo, Hatch, Jones, Kendall, Kheifets, Kheifets, Kheifets, Kinlen, Kleinerman, L. Kheifets, Lupo, M. Cockburn, Madsen, McBride, McCarthy, Mezei, O.A. Arah, Oksuzyan, Oksuzyan, Oksuzyan, Rosenbaum, S. Oksuzyan, Sahl, Schoendorf, Schulman, Stiller, Swanson, Urayama, Vergara, Wartenberg, X. Vergara, Yost   +44 more
core   +3 more sources

Automated Detection of Acute Lymphoblastic Leukemia Subtypes from Microscopic Blood Smear Images using Deep Neural Networks [PDF]

arXiv, 2022
An estimated 300,000 new cases of leukemia are diagnosed each year which is 2.8 percent of all new cancer cases and the prevalence is rising day by day. The most dangerous and deadly type of leukemia is acute lymphoblastic leukemia (ALL), which affects people of all age groups, including children and adults.
arxiv  

Ultra-deep sequencing leads to earlier and more sensitive detection of the tyrosine kinase inhibitor resistance mutation T315I in chronic myeloid leukemia

Haematologica, 2016
Chronic myeloid leukemia cells acquire resistance to tyrosine kinase inhibitors through mutations in the ABL1 kinase domain. The T315I mutation mediates resistance to imatinib, dasatinib, nilotinib and bosutinib, whereas sensitivity to ponatinib remains.
Constance Baer, Wolfgang Kern, Sarah Koch, Niroshan Nadarajah, Sonja Schindela, Manja Meggendorfer, Claudia Haferlach, Torsten Haferlach   +7 more
doaj   +1 more source

Preleukemia: hematological disorders prior to onset of leukemia [PDF]

, 1975
Published data on Japanese leukemia patients with a preleukemic hematological disorder were assessed. The reexamined cases were from the "Japona Centra Revuo Medicina" reported during the period from 1952 to 1971.
Hiraki, Kiyoshi, Kitajima, Koichi, Mikochi, Hiroshi, Nakanishi, Toshio, Sakato, Junya, Takahashi, Isao   +5 more
core   +1 more source