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2020
Leukemia is a malignant clonal disease that originates from hematopoietic stem cells. As in-depth research examines the molecular biology and immunology of the hematopoietic system, leukemia treatment has evolved from a single cytotoxic drug to treatments that inducing differentiation and apoptosis.
Wei-Li Zhao +4 more
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Leukemia is a malignant clonal disease that originates from hematopoietic stem cells. As in-depth research examines the molecular biology and immunology of the hematopoietic system, leukemia treatment has evolved from a single cytotoxic drug to treatments that inducing differentiation and apoptosis.
Wei-Li Zhao +4 more
openaire +2 more sources
Myelodysplasia and the leukemias
Current Problems in Cancer, 1997The armistice after World War II marked the beginning of an era that was to last to the end of the present century. It was an era in which many changes in medicine and nursing combined to alter the entire philosophy of managing malignant disease. More specifically, the fluid-phase tumors, which comprise myelodysplasia and the leukemias, were singled ...
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Pediatric Clinics of North America, 1997
Advances in the molecular and immunologic characterization of leukemic cells have greatly aided the diagnosis and risk assignment of ALL, as well as the monitoring of bone marrow samples for minimal residual disease. Currently, 75% of childhood cases have biologically and therapeutically relevant genetic abnormalities.
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Advances in the molecular and immunologic characterization of leukemic cells have greatly aided the diagnosis and risk assignment of ALL, as well as the monitoring of bone marrow samples for minimal residual disease. Currently, 75% of childhood cases have biologically and therapeutically relevant genetic abnormalities.
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Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2000
Heather Thompson Mackey, Paula Klemm
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Heather Thompson Mackey, Paula Klemm
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Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
Science, 2004A. Weng +8 more
semanticscholar +1 more source
2005
Publisher Summary Most cases of leukemia do not stem from an inherited genetic predisposition but from somatic genetic alterations. The etiology of acute leukemia is unknown. The factors are important in the pathogenesis of leukemia have been highlighted in this chapter.
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Publisher Summary Most cases of leukemia do not stem from an inherited genetic predisposition but from somatic genetic alterations. The etiology of acute leukemia is unknown. The factors are important in the pathogenesis of leukemia have been highlighted in this chapter.
openaire +2 more sources