Results 31 to 40 of about 1,683,745 (416)

Leukemia detection based on microscopic blood smear images using deep learning [PDF]

arXiv, 2022
In this paper we discuss a new method for detecting leukemia in microscopic blood smear images using deep neural networks to diagnose leukemia early in blood. leukemia is considered one of the most dangerous mortality causes for a human being, the traditional process of diagnosis of leukemia in blood is complex, costly, and time-consuming, so patients ...
arxiv  

Genomic aberrations and survival in chronic lymphocytic leukemia.

New England Journal of Medicine, 2000
BACKGROUND Fluorescence in situ hybridization has improved the detection of genomic aberrations in chronic lymphocytic leukemia. We used this method to identify chromosomal abnormalities in patients with chronic lymphocytic leukemia and assessed their ...
H. Döhner, S. Stilgenbauer, A. Benner, E. Leupolt, A. Kröber, L. Bullinger, K. Döhner, Martin Bentz, P. Lichter   +8 more
semanticscholar   +1 more source

Phase 1 study of an anti-CD33 immunotoxin, humanized monoclonal antibody M195 conjugated to recombinant gelonin (HUM-195/rGEL), in patients with advanced myeloid malignancies

Haematologica, 2013
We conducted a phase 1 study of an anti-CD33 immunotoxin, humanized monoclonal antibody M195 conjugated to recombinant gelonin (HUM-195/rGEL), in patients with relapsed, refractory myeloid leukemias.
Gautam Borthakur, Michael G. Rosenblum, Moshe Talpaz, Naval Daver, Farhad Ravandi, Stefan Faderl, Emil J. Freireich, Tapan Kadia, Guillermo Garcia-Manero, Hagop Kantarjian, Jorge E. Cortes   +10 more
doaj   +1 more source

A study on the isolation of leukemia virus of AKR mouse by fluorocarbon [PDF]

, 1962
The authors have succeeded in isolating a biologically-active leukemia virus from leukemic tissues of AKR mice with a fluorocarbon. From the chemical analysis of the biologically-active virus fraction it has been clarified that the AKR leukemia virus is ...
Miyoshi, Isao, Okada, Koichi
core   +1 more source

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.

New England Journal of Medicine, 2011
We designed a lentiviral vector expressing a chimeric antigen receptor with specificity for the B-cell antigen CD19, coupled with CD137 (a costimulatory receptor in T cells [4-1BB]) and CD3-zeta (a signal-transduction component of the T-cell antigen ...
D. Porter, B. Levine, M. Kalos, A. Bagg, C. June   +4 more
semanticscholar   +1 more source

Molecular analyses of 15,542 patients with suspected BCR-ABL1-negative myeloproliferative disorders allow to develop a stepwise diagnostic workflow

Haematologica, 2012
We investigated 15,542 patients with suspected BCR-ABL1- negative myeloproliferative or myelodysplastic/myeloproliferative neoplasm (including 359 chronic myelomonocytic leukemia) by a molecular marker set.
Susanne Schnittger, Ulrike Bacher, Christiane Eder, Frank Dicker, Tamara Alpermann, Vera Grossmann, Alexander Kohlmann, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach   +9 more
doaj   +1 more source

Chimeric antigen receptor-modified T cells for acute lymphoid leukemia.

New England Journal of Medicine, 2013
Chimeric antigen receptor-modified T cells with specificity for CD19 have shown promise in the treatment of chronic lymphocytic leukemia (CLL). It remains to be established whether chimeric antigen receptor T cells have clinical activity in acute ...
Stephan A Grupp, M. Kalos, D. Barrett, R. Aplenc, David L. Porter, S. Rheingold, D. Teachey, A. Chew, B. Hauck, J. F. Wright, Michael C. Milone, Bruce L. Levine, Carl H June   +12 more
semanticscholar   +1 more source

Association between Outdoor Air Pollution and Childhood Leukemia: A Systematic Review and Dose-Response Meta-Analysis. [PDF]

, 2019
BackgroundA causal link between outdoor air pollution and childhood leukemia has been proposed, but some older studies suffer from methodological drawbacks.
Abdul Rahman HI, Alessio Crippa, Andreoli R, Andrew S. Park, Elizabeth E. Hatch, IARC, IARC (International Agency for Research on Cancer), Julia E. Heck, Kenneth J. Rothman, Marco Vinceti, Nicola Orsini, Tommaso Filippini   +11 more
core   +1 more source

Residential mobility and childhood leukemia. [PDF]

, 2018
AimsStudies of environmental exposures and childhood leukemia studies do not usually account for residential mobility. Yet, in addition to being a potential risk factor, mobility can induce selection bias, confounding, or measurement error in such ...
A.T. Amoon, Alba, C.M. Crespi, Canfield, Champion, Charles, Chen, Clark, Clark, Crespi, Feychting, Goldberg, Green, Guo, Hatch, Jones, Kendall, Kheifets, Kheifets, Kheifets, Kinlen, Kleinerman, L. Kheifets, Lupo, M. Cockburn, Madsen, McBride, McCarthy, Mezei, O.A. Arah, Oksuzyan, Oksuzyan, Oksuzyan, Rosenbaum, S. Oksuzyan, Sahl, Schoendorf, Schulman, Stiller, Swanson, Urayama, Vergara, Wartenberg, X. Vergara, Yost   +44 more
core   +3 more sources

Molecular methods for genomic analyses of variant PML-RARA or other RARA-related chromosomal translocations in acute promyelocytic leukemia [PDF]

, 2012
TO THE EDITOR: We read an interesting paper by Palta et al. in a recent issue of the Korean Journal of Hematology titled, "ZBTB16-RARA variant of acute promyelocytic leukemia with tuberculosis: a case report and review of literature" [1].
Kim, Min Jin, Marschalek, Rolf, Meyer, Claus, Park, Tae Sung, Yang, John Jeongseok   +4 more
core   +1 more source