Results 1 to 10 of about 69,360 (221)

DHX15 inhibits mouse APOBEC3 deamination. [PDF]

PLoS Pathogens
APOBEC3 family proteins are critical host factors that counteract and prevent the replication of retroviruses and other viruses through cytidine deamination.
Wenming Zhao, Ayan Modak, Susan R Ross
doaj   +2 more sources

DNA extraction columns contaminated with murine sequences. [PDF]

PLoS ONE, 2011
Sequences of the novel gammaretrovirus, xenotropic murine leukemia virus-related virus (XMRV) have been described in human prostate cancer tissue, although the amounts of DNA are low. Furthermore, XMRV sequences and polytropic (p) murine leukemia viruses
Otto Erlwein, Mark J Robinson, Simon Dustan, Jonathan Weber, Steve Kaye, Myra O McClure   +5 more
doaj   +1 more source

Murine leukemia virus (MLV) P50 protein induces cell transformation via transcriptional regulatory function

Retrovirology, 2023
Background The murine leukemia virus (MLV) has been a powerful model of pathogenesis for the discovery of genes involved in cancer. Its splice donor (SD’)-associated retroelement (SDARE) is important for infectivity and tumorigenesis, but the mechanism ...
Charbel Akkawi, Jerome Feuillard, Felipe Leon Diaz, Khalid Belkhir, Nelly Godefroy, Jean-Marie Peloponese, Marylene Mougel, Sebastien Laine   +7 more
doaj   +1 more source

Murine gammaretrovirus group G3 was not found in Swedish patients with myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia. [PDF]

PLoS ONE, 2011
BACKGROUND: The recent report of gammaretroviruses of probable murine origin in humans, called xenotropic murine retrovirus related virus (XMRV) and human murine leukemia virus related virus (HMRV), necessitated a bioinformatic search for this virus in ...
Amal Elfaitouri, Xingwu Shao, Johan Mattsson Ulfstedt, Shaman Muradrasoli, Agnes Bölin Wiener, Sultan Golbob, Christina Ohrmalm, Michael Matousek, Olof Zachrisson, Carl-Gerhard Gottfries, Jonas Blomberg   +10 more
doaj   +1 more source

Tumorigenesis related to retroviral infections

Journal of Infection in Developing Countries, 2011
Retroviral infections are considered important risk factors for cancer development in humans since approximately 15-20% of cancer worldwide is caused by an infectious agent.
Maria Braoudaki, Fotini Tzortzatou-Stathopoulou   +1 more
doaj   +1 more source

Xenotropic murine leukemia virus-related virus is not associated with chronic fatigue syndrome in patients from different areas of the us in the 1990s

Virology Journal, 2011
Background In 2009, xenotropic murine leukemia virus-related virus (XMRV) was reported in 67% of patients with chronic fatigue syndrome (CFS) compared to 4% of controls.
Miller Frederick W, Goldbach-Mansky Raphaela, Kozak Christine A, Dale Janet K, Ali Mir A, Straus Stephen E, Cohen Jeffrey I   +6 more
doaj   +1 more source

Antibody responses against xenotropic murine leukemia virus-related virus envelope in a murine model. [PDF]

PLoS ONE, 2011
Xenotropic murine leukemia virus-related virus (XMRV) was recently discovered to be the first human gammaretrovirus that is associated with chronic fatigue syndrome and prostate cancer (PC).
Natalia Makarova, Chunxia Zhao, Yuanyuan Zhang, Sushma Bhosle, Suganthi Suppiah, Jeanne M Rhea, Natalia Kozyr, Rebecca S Arnold, Hinh Ly, Ross J Molinaro, Tristram G Parslow, Eric Hunter, Dennis Liotta, John Petros, Jerry L Blackwell   +14 more
doaj   +1 more source

Co-infection with the friend retrovirus and mouse scrapie does not alter prion disease pathogenesis in susceptible mice. [PDF]

PLoS ONE, 2012
Prion diseases are fatal, transmissible neurodegenerative diseases of the central nervous system. An abnormally protease-resistant and insoluble form (PrP(Sc)) of the normally soluble protease-sensitive host prion protein (PrP(C)) is the major component ...
Pascal Leblanc, Kim Hasenkrug, Anne Ward, Lara Myers, Ronald J Messer, Sandrine Alais, Andrew Timmes, Suzette A Priola   +7 more
doaj   +1 more source

Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus

Retrovirology, 2007
Background Mutations of an alternative splice donor site located within the gag region has previously been shown to broaden the pathogenic potential of the T-lymphomagenic gammaretrovirus Moloney murine leukemia virus, while the equivalent mutations in ...
Quintanilla-Martinez Leticia, Kunder Sandra, Lund Anders H, Sørensen Annette, Schmidt Jörg, Wang Bruce, Wabl Matthias, Pedersen Finn   +7 more
doaj   +1 more source

Lack of infection with XMRV or other MLV-related viruses in blood, post-mortem brains and paternal gametes of autistic individuals. [PDF]

PLoS ONE, 2011
BackgroundAutistic spectrum disorder (ASD) is characterized by impaired language, communication and social skills, as well as by repetitive and stereotypic patterns of behavior. Many autistic subjects display a dysregulation of the immune system which is
Carla Lintas, Francesco Guidi, Barbara Manzi, Antonio Mancini, Paolo Curatolo, Antonio M Persico   +5 more
doaj   +1 more source