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The Immunoproteasome Is Expressed but Dispensable for a Leukemia Infected Cell Vaccine [PDF]

Vaccines
Background/Objectives: Leukemia is associated with high recurrence rates and cancer vaccines are emerging as a promising immunotherapy against the disease.
Delphine Béland, Victor Mullins-Dansereau, Karen Geoffroy, Mélissa Viens, Kim Leclerc Desaulniers, Marie-Claude Bourgeois-Daigneault   +5 more
doaj   +2 more sources

Murine leukemia virus (MLV) P50 protein induces cell transformation via transcriptional regulatory function

Retrovirology, 2023
Background The murine leukemia virus (MLV) has been a powerful model of pathogenesis for the discovery of genes involved in cancer. Its splice donor (SD’)-associated retroelement (SDARE) is important for infectivity and tumorigenesis, but the mechanism ...
Charbel Akkawi, Jerome Feuillard, Felipe Leon Diaz, Khalid Belkhir, Nelly Godefroy, Jean-Marie Peloponese, Marylene Mougel, Sebastien Laine   +7 more
doaj   +1 more source

DNA extraction columns contaminated with murine sequences. [PDF]

PLoS ONE, 2011
Sequences of the novel gammaretrovirus, xenotropic murine leukemia virus-related virus (XMRV) have been described in human prostate cancer tissue, although the amounts of DNA are low. Furthermore, XMRV sequences and polytropic (p) murine leukemia viruses
Otto Erlwein, Mark J Robinson, Simon Dustan, Jonathan Weber, Steve Kaye, Myra O McClure   +5 more
doaj   +1 more source

Murine gammaretrovirus group G3 was not found in Swedish patients with myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia. [PDF]

PLoS ONE, 2011
BACKGROUND: The recent report of gammaretroviruses of probable murine origin in humans, called xenotropic murine retrovirus related virus (XMRV) and human murine leukemia virus related virus (HMRV), necessitated a bioinformatic search for this virus in ...
Amal Elfaitouri, Xingwu Shao, Johan Mattsson Ulfstedt, Shaman Muradrasoli, Agnes Bölin Wiener, Sultan Golbob, Christina Ohrmalm, Michael Matousek, Olof Zachrisson, Carl-Gerhard Gottfries, Jonas Blomberg   +10 more
doaj   +1 more source

Tumorigenesis related to retroviral infections

Journal of Infection in Developing Countries, 2011
Retroviral infections are considered important risk factors for cancer development in humans since approximately 15-20% of cancer worldwide is caused by an infectious agent.
Maria Braoudaki, Fotini Tzortzatou-Stathopoulou   +1 more
doaj   +1 more source

In vitro transformation of lymphoid cells by Abelson murine leukemia virus [PDF]

, 1975
Cell cultures prepared from fetal murine liver were infected by Abelson murine leukemia virus. After about 2 weeks, proliferating cells of lymphoid morphology appeared in some of the cultures.
Baltimore, David, Rosenberg, Naomi, Scher, Charles D.   +2 more
core   +2 more sources

Xenotropic murine leukemia virus-related virus is not associated with chronic fatigue syndrome in patients from different areas of the us in the 1990s

Virology Journal, 2011
Background In 2009, xenotropic murine leukemia virus-related virus (XMRV) was reported in 67% of patients with chronic fatigue syndrome (CFS) compared to 4% of controls.
Miller Frederick W, Goldbach-Mansky Raphaela, Kozak Christine A, Dale Janet K, Ali Mir A, Straus Stephen E, Cohen Jeffrey I   +6 more
doaj   +1 more source

Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response. [PDF]

, 2011
Members of the APOBEC3 family of deoxycytidine deaminases counteract a broad range of retroviruses in vitro through an indirect mechanism that requires virion incorporation and inhibition of reverse transcription and/or hypermutation of minus strand ...
Barrett, Bradley S, Evans, Leonard H, Greene, Warner C, Guo, Kejun, Hasenkrug, Kim J, Heilman, Karl J, Santiago, Mario L, Smith, Diana S   +7 more
core   +8 more sources

Antibody responses against xenotropic murine leukemia virus-related virus envelope in a murine model. [PDF]

PLoS ONE, 2011
Xenotropic murine leukemia virus-related virus (XMRV) was recently discovered to be the first human gammaretrovirus that is associated with chronic fatigue syndrome and prostate cancer (PC).
Natalia Makarova, Chunxia Zhao, Yuanyuan Zhang, Sushma Bhosle, Suganthi Suppiah, Jeanne M Rhea, Natalia Kozyr, Rebecca S Arnold, Hinh Ly, Ross J Molinaro, Tristram G Parslow, Eric Hunter, Dennis Liotta, John Petros, Jerry L Blackwell   +14 more
doaj   +1 more source

The effect of helper virus on Abelson virus-induced transformation of lymphoid cells [PDF]

, 1978
Abelson murine leukemia virus (A-MuLV)-transformed fibroblast nonproducer cells were used to prepare A-MuLV stocks containing a number of different helper viruses.
Baltimore, David, Rosenberg, Naomi
core   +2 more sources