Results 181 to 190 of about 166,376 (296)

Long non‐coding RNA lncAPAT promotes atherosclerotic plaque instability by targeting ribosomal protein L22

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
LncAPAT interacted with the promoter region of RPL22 to inhibit RPL22 transcriptional activity and increase the expression of MCP‐1, thereby contributing to plaque instability. Abstract Background Long non‐coding RNAs (lncRNAs) regulate macrophage inflammation and atherosclerotic plaque stability, but mechanisms need comprehensive investigations ...
Rongxia Li, Qiyue Zhang, Yu Chen, Shuting Wang, Shuang Han, Adalaiti Kamili, Yixuan Zhong, Shujun Yang, Weili Zhang   +8 more
wiley   +1 more source

Characterization of Murine Leukemia Virus-specific Proteins

Cold Spring Harbor Symposia on Quantitative Biology, 1974
E, Fleissner, H, Ikeda, J S, Tung, E S, Vitetta, E, Tress, W, Hardly, E, Stockert, E A, Boyse, T, Pincus, P, O'Donnell   +9 more
openaire   +2 more sources

Natural Products Targeting the EGFR/HER2 Axis in Tumorigenesis: Interpretation of Molecular Mechanisms and Recent Insights Into Synergistic Strategies for Cancer Therapy

Food Frontiers, Volume 7, Issue 1, January 2026.
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli, Anna Maria Posadino, Roberta Giordo, Antonio Barberis, Ylenia Spissu, Redouane Lemoui, William N. Setzer, Javad Sharifi‐Rad, Gianfranco Pintus   +8 more
wiley   +1 more source

Ex Vivo Gene and Cell Therapy in Hematopoietic Stem Cells. [PDF]

Int J Mol Sci
Petrova IO, Smirnikhina SA.
europepmc   +1 more source

Almond Polysaccharide Ameliorates DSS‐Induced Ulcerative Colitis in Mice by Restoring Intestinal Barrier Function and Modulating Gut Microbiota and SCFAs Metabolism

Food Frontiers, Volume 7, Issue 1, January 2026.
This study shows that almond polysaccharide AP1 relieves DSS‐induced UC in mice by restoring the mucosal barrier, suppressing inflammation, and modulating gut microbiota and SCFA metabolism. ABSTRACT The development of new therapeutic strategies for ulcerative colitis (UC) requires the targeting of multiple pathogenic factors, including disruption of ...
Yanqi Peng, Ji Wu, Ronghua Fan, Mingyue Ma, Xixin Wang, Yuzhen Pi, Xiqing Yue, Yanyu Peng   +7 more
wiley   +1 more source

Regulatory role of mTORC1 signaling in osteoblasts in acute myeloid leukemia progression and steady-state hematopoiesis. [PDF]

iScience
Fukasawa K, Tokumura K, Yoshimoto M, Sadamori K, Mosialou I, Harakawa Y, Isawa K, Tsuji S, Inufusa H, Hirao A, Kousteni S, Hinoi E.   +11 more
europepmc   +1 more source

Foreign H-2-like ,olecules on a murine tumor (MCG4) [PDF]

, 1980
Garcia-Olivares, E., Garrido, F., Hübsch, D., Koszinowski, Ulrich H., Schirrmacher, V.   +4 more
core   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, Volume 7, Issue 1, January 2026.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Viral zoonosis and human cancer: a perspective. [PDF]

Infect Agent Cancer
Aguayo F.
europepmc   +1 more source

Tet2 deficiency promotes IgG1+ B‐cell expansion and differentiation blockade through deregulation of the Nfkbia–c‐Rel axis

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract The germinal center (GC) reaction is essential for orchestrating humoral immunity by producing plasma cells (PCs) and memory B cells (MBCs). TET2, an α‐ketoglutarate‐dependent dioxygenase, plays a critical role in B‐cell exit from the GC and in plasma cell differentiation.
Hussein Ghamlouch, Michaël Degaud, Veronique Della‐Valle, Alexandre Eeckhoutte, Marine Armand, Amina Joudat, Camille Decaudin, Pilar M. Dominguez, Wojciech Rosikiewicz, Patrycja Pawlikowska, Walaa Darwiche, Enguerran Mouly, Sheng Li, Ari M. Melnick, Said Aoufouchi, Olivier A. Bernard   +15 more
wiley   +1 more source