Results 201 to 210 of about 166,376 (296)

Development of a Porcine Cell Line Stably Expressing Ephrin‐B2 for Nipah Virus Research and Diagnostic Testing

open access: yesMicrobiology and Immunology, Volume 70, Issue 1, Page 36-46, January 2026.
ABSTRACT Nipah virus (NiV) is a highly pathogenic zoonotic virus transmitted from bats to humans through pigs as a crucial intermediate host. NiV outbreaks pose significant public health and economic threats, especially for pig farmers. Although the World Organization for Animal Health recommends African green monkey‐derived Vero cells for NiV ...
Hui Zhang, Akatsuki Saito
wiley   +1 more source

Humanized Mouse Models as a Cellular Platform for Investigating Immune‐Hormonal Crosstalk and Therapeutic Strategies in Menopause

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
Humanized mice offer new insight into immune‐hormonal changes during menopause. Traditional models lack accuracy in replicating human menopause physiology. Functional foods may ease symptoms but need testing in human‐relevant systems. Combining humanized mice with diet research can improve women's health outcomes.
Nisansala Chandimali   +6 more
wiley   +1 more source

β‐Hydroxybutyrate Acts as an Exercise Mimetic to Protect the Aging Liver

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
β‐hydroxybutyrate (β‐HB) acts as an exercise mimetic to protect the aging liver. In aged models, exercise‐induced β‐HB delays liver aging by reversing macrophage senescence, blocking mtDNA/cGAS‐STING‐driven inflammation, and alleviating hepatocyte lipid deposition/PANoptosis.
Ke Li   +7 more
wiley   +1 more source

Senolytic Treatment With Dasatinib and Quercetin Reshapes Influenza‐Specific CD8 T Cell Responses During Infection in Aged, Vaccinated Mice

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
Impaired vaccination responses leave older adults more vulnerable to severe influenza (flu) infections. Pretreatment with senolytic Dasatinib and Quercertin (D + Q) did not improve vaccine responses but altered some responses to sublethal flu challenge. Despite these changes, overall flu outcomes were not impacted.
Andreia N. Cadar   +10 more
wiley   +1 more source

In vivo CAR cell therapy: from bench to bedside. [PDF]

open access: yesJ Hematol Oncol
Xu J, Chen Z, Su L, Ren A, Mei H.
europepmc   +1 more source

ZNF282 Promotes Colorectal Cancer Progression Possibly via E2F1 Activation

open access: yesCancer Science, Volume 117, Issue 1, Page 90-104, January 2026.
ZNF282 is a zinc finger protein overexpressed in colorectal cancer that facilitates tumor progression by promoting cell cycle progression via E2F1 activation. Our study demonstrates that ZNF282 expression is associated with poor prognosis and may serve as a novel prognostic biomarker and therapeutic target. ABSTRACT Colorectal cancer (CRC) is a leading
Tadashi Abe   +23 more
wiley   +1 more source

Home - About - Disclaimer - Privacy