Results 21 to 30 of about 69,360 (221)

Endogenous Murine Leukemia Viruses: Relationship to XMRV and Related Sequences Detected in Human DNA Samples

open access: yesAdvances in Virology, 2011
Xenotropic-murine-leukemia-virus-related virus (XMRV) was the first gammaretrovirus to be reported in humans. The sequence similarity between XMRV and murine leukemia viruses (MLVs) was consistent with an origin of XMRV from one or more MLVs present as ...
Oya Cingöz, John M. Coffin
doaj   +1 more source

Frequent Infection of Human Cancer Xenografts with Murine Endogenous Retroviruses in Vivo

open access: yesViruses, 2015
Infection of human cancer xenografts in mice with murine leukemia viruses (MLVs) is a long-standing observation, but the likelihood of infection in vivo and its biological consequences are poorly understood.
Asif Naseer   +10 more
doaj   +1 more source

The saga of XMRV: a virus that infects human cells but is not a human virus

open access: yesEmerging Microbes and Infections, 2014
Xenotropic murine leukemia virus-related virus (XMRV) was discovered in 2006 in a search for a viral etiology of human prostate cancer (PC). Substantial interest in XMRV as a potentially new pathogenic human retrovirus was driven by reports that XMRV ...
Maribel Arias, Hung Fan
doaj   +1 more source

Phylogenetic Relationship of the Complete Rauscher Murine Leukemia Virus Genome with Other Murine Leukemia Virus Genomes

open access: yesVirology, 1997
We report the complete nucleotide sequence of the genome of Rauscher murine leukemia virus (R-MuLV), the replication-competent helper virus present in the Rauscher virus complex, and its phylogenetic relationship with other murine leukemia virus genomes. An overall sequence identity of 97.6% was found between R-MuLV and the Friend helper virus (F-MuLV),
Temple F. Smith   +4 more
openaire   +3 more sources

Absence of XMRV and closely related viruses in primary prostate cancer tissues used to derive the XMRV-infected cell line 22Rv1. [PDF]

open access: yesPLoS ONE, 2012
The 22Rv1 cell line is widely used for prostate cancer research and other studies throughout the world. These cells were established from a human prostate tumor, CWR22, that was serially passaged in nude mice and selected for androgen independence.
Jaydip Das Gupta   +7 more
doaj   +1 more source

Transplacental transmission of a leukemogenic murine leukemia virus [PDF]

open access: yesJournal of Virology, 1993
Recombinant inbred BXH-2 mice spontaneously produce a B-tropic murine leukemia virus (MuLV) beginning early in life and have a high incidence of spontaneous myeloid leukemia. These traits are not characteristic of the progenitor strains (C57BL/6J and C3H/HeJ) or of 11 other recombinant inbred BXH strains.
Bedigian, H G, Shepel, L A, Hoppe, P C
openaire   +3 more sources

No association between XMRV or related gammaretroviruses in Australian prostate cancer patients

open access: yesVirology Journal, 2013
Background Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with prostate cancer (PC) and chronic fatigue syndrome (CFS).
Rezaei Simin D   +4 more
doaj   +1 more source

Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein. [PDF]

open access: yesPLoS Genetics, 2008
Intrinsic immunity relies on specific recognition of viral epitopes to mount a cell-autonomous defense against viral infections. Viral recognition determinants in intrinsic immunity genes are expected to evolve rapidly as host genes adapt to changing ...
Julie A Kerns   +2 more
doaj   +1 more source

Structure and Leukemogenic Activity of a Murine Leukemia Virus [PDF]

open access: yesJournal of Virology, 1968
Purified Friend viruses obtained from chronically infected tissue cultures were studied under the electron microscope in an effort to correlate the fine structure of the particles to their leukemogenic activity under varied experimental conditions, i.e., temperature treatments and exposure to Tween 80, amyl acetate, or ether.
Charlotte Friend   +5 more
openaire   +3 more sources

Characterization of Leukemia-Inducing Genes Using a Proto-Oncogene/Homeobox Gene Retroviral Human cDNA Library in a Mouse In Vivo Model. [PDF]

open access: yesPLoS ONE, 2015
The purpose of this research is to develop a method to screen a large number of potential driver mutations of acute myeloid leukemia (AML) using a retroviral cDNA library and murine bone marrow transduction-transplantation system.
Su Hwa Jang, Sohyun Lee, Hee Yong Chung
doaj   +1 more source

Home - About - Disclaimer - Privacy