Lack of class I H-2 antigens in cells transformed by radiation leukemia virus is associated with methylation and rearrangement of H-2 DNA [PDF]
, 1986 Transformation of murine thymocytes by radiation leukemia virus is associated with reduced expression of the class I antigens encoded in the major histocompatibility complex (MHC) and increased methylation and altered restriction enzyme patterns of MHC ...
Boral, Anthony +11 more
core +1 more source
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
Advances in Virology, 2011 Xenotropic-murine-leukemia-virus-related virus (XMRV) was the first gammaretrovirus to be reported in humans. The sequence similarity between XMRV and murine leukemia viruses (MLVs) was consistent with an origin of XMRV from one or more MLVs present as ...
Oya Cingöz, John M. Coffin
doaj +1 more source
Prevalence and characterization of murine leukemia virus contamination in human cell lines. [PDF]
PLoS ONE, 2015 Contaminations of cell cultures with microbiological organisms are well documented and can be managed in cell culture laboratories applying reliable detection, elimination and prevention strategies.
Cord C Uphoff +4 more
doaj +1 more source
Frequent Infection of Human Cancer Xenografts with Murine Endogenous Retroviruses in Vivo
Viruses, 2015 Infection of human cancer xenografts in mice with murine leukemia viruses (MLVs) is a long-standing observation, but the likelihood of infection in vivo and its biological consequences are poorly understood.
Asif Naseer +10 more
doaj +1 more source
A quantitative assay for transformation of bone marrow cells by Abelson murine leukemia virus [PDF]
, 1976 A quantitative Abelson murine leukemia virus (A-MuLV) lymphoid cell transformation assay has been developed using a semisolid agarose culture system. Under these conditions lymphoid cell transformation was shown to vary linearly with the dose of A-MuLV ...
Baltimore, David, Rosenberg, Naomi
core +1 more source
The saga of XMRV: a virus that infects human cells but is not a human virus
Emerging Microbes and Infections, 2014 Xenotropic murine leukemia virus-related virus (XMRV) was discovered in 2006 in a search for a viral etiology of human prostate cancer (PC). Substantial interest in XMRV as a potentially new pathogenic human retrovirus was driven by reports that XMRV ...
Maribel Arias, Hung Fan
doaj +1 more source
Absence of XMRV and closely related viruses in primary prostate cancer tissues used to derive the XMRV-infected cell line 22Rv1. [PDF]
PLoS ONE, 2012 The 22Rv1 cell line is widely used for prostate cancer research and other studies throughout the world. These cells were established from a human prostate tumor, CWR22, that was serially passaged in nude mice and selected for androgen independence.
Jaydip Das Gupta +7 more
doaj +1 more source
No association between XMRV or related gammaretroviruses in Australian prostate cancer patients
Virology Journal, 2013 Background Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with prostate cancer (PC) and chronic fatigue syndrome (CFS).
Rezaei Simin D +4 more
doaj +1 more source
Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein. [PDF]
PLoS Genetics, 2008 Intrinsic immunity relies on specific recognition of viral epitopes to mount a cell-autonomous defense against viral infections. Viral recognition determinants in intrinsic immunity genes are expected to evolve rapidly as host genes adapt to changing ...
Julie A Kerns +2 more
doaj +1 more source