Results 191 to 200 of about 183,662 (252)

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

Advanced Science, EarlyView.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez, Nicholas Basista, Sudhanshu Mishra, Hyeri Kim, Audrey Bench, Catherine Matte‐Martone, Min‐Soo Seo, Gun Woo Lee, Sangbum Park   +8 more
wiley   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source

[Differential counting of leukocytes].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2016
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

The leukocyte count in labor

American Journal of Obstetrics and Gynecology, 1985
The leukocyte count was evaluated in 479 laboring gravida women. Increasing leukocyte counts appeared to be linearly related to the duration of elapsed labor (y = 0.2174x + 10.31; p less than 0.001; 95% confidence interval of the slope = 0.1414 to 0.2934).
Benjamin P Sachs, Emanuel A Friedman, M P Johnson   +2 more
exaly   +3 more sources

The Leukocyte Count and Cancer Mortality

American Journal of Epidemiology, 1991
A previous report that the leukocyte count was related to mortality from cancer was evaluated in two large groups of multiphasic health examinees in the San Francisco Bay area, California--a cohort of about 25,000 persons followed up for mortality and a cohort of about 160,000 persons followed up for cancer incidence between 1964 and 1980.
Bruce Fireman, Gary D Friedman, Fireman Bruce H   +2 more
exaly   +3 more sources

Smoking Habits and the Leukocyte Count

Archives of Environmental Health: An International Journal, 1973
In 86,488 multiphasic examinations, mean leukocyte counts were highest in cigarette smokers, intermediate in ex-cigarette and cigar or pipe smokers, and lowest in nonsmokers. Among the races, whites had the highest, yellows next, and blacks the lowest leukocyte counts. The leukocyte count was related to quantity smoked, inhalation, and smoking duration.
G D, Friedman, A B, Siegelaub, C C, Seltzer, R, Feldman, M F, Collen   +4 more
openaire   +4 more sources

Leukocyte counts and cerebrovascular disease

Journal of Chronic Diseases, 1982
Elevated total leukocyte count in a biennial examination period is shown to be a significant (p = 0.001) predictor of cerebral infarction (CI) incidence in the subsequent 2 yr examination period, in a large Japanese cohort study. This association is not explainable on the basis of corresponding age, sex or blood pressure levels. The extent to which the
R L, Prentice, T P, Szatrowski, H, Kato, M W, Mason   +3 more
openaire   +2 more sources