Results 281 to 290 of about 258,333 (346)

Autologous Organoid‐T Cell Co‐Culture Platform for Modeling of Immune‐Mediated Drug‐Induced Liver Injury

open access: yesAdvanced Science, EarlyView.
A matrix‐free human liver organoid–T cell co‐culture platform enables modeling of immune‐mediated drug‐induced liver injury (iDILI). Using flucloxacillin and patient‐matched cells, this system recapitulates HLA‐B*57:01–restricted CD8⁺ T cell activation and hepatocyte damage.
Fadoua El Abdellaoui Soussi   +11 more
wiley   +1 more source

Effect of remobinant granulocyte-macrophage colony stimulating factor (GM-CSF) on leukopenia in AIDS [PDF]

open access: yes, 1991
Bogner, Johannes R.   +7 more
core  

Self‐Propelled Magnetic Micromotor‐Functionalized DNA Tile System for Autonomous Capture of Circulating Tumor Cells in Clinical Diagnostics

open access: yesAdvanced Science, EarlyView.
The magnetic micromotor‐functionalized DNA‐array hunter (MMDA hunter), integrating autonomous propulsion and precision‐partitioned functionalities, utilizes DNA array programmability and 5'‐3' directional control to achieve spatially partitioned module arrangement.
Qiumei Pu   +15 more
wiley   +1 more source

Polydopamine Nanodots Ameliorate Inflammatory Bowel Disease by Restoring Redox Homeostasis and Intestinal Microenvironment

open access: yesAdvanced Science, EarlyView.
A novel melanin‐based therapeutic composed of ultrasmall polydopamine nanodots is employed as an efficient oral formulation for the targeted treatment of inflammatory bowel disease. The potential therapeutic mechanism of polydopamine nanodots mainly involves the elimination of excessive oxidative stress, the reduction of ROS‐mediated proinflammatory ...
Zhen Ding   +11 more
wiley   +1 more source

NIR‐II Responsive Multifunctional Scaffold Enabling “Kill‐Modulation‐Build” Synergistic Therapy for Infectious Bone Defects

open access: yesAdvanced Science, EarlyView.
A novel multifunctional scaffold with photothermal effects is developed for infected bone defect repair. It facilitates angiogenesis and osteogenesis while eliminating bacteria through hyperthermia. Additionally, the scaffold promotes macrophage polarization from M1 to M2 via ROS scavenging, enhancing anti‐inflammatory activity. This study demonstrates
Qifei Yang   +9 more
wiley   +1 more source

Concrete Structure Inspired 3D‐Printed Framework Mechanically Reinforced Zwitterionic Hydrogel for Efficient Postoperative Abdominal Adhesion Prevention

open access: yesAdvanced Science, EarlyView.
Inspired by the establishment process and structure of concrete, a 3D‐printed PCL framework‐reinforced composite hydrogel is developed to overcome the mechanical limits of the original zwitterionic hydrogel toward clinic application of postoperative adhesion prevention.
Jianguo Song   +4 more
wiley   +1 more source

Leukocyte count: A reliable marker for the severity of organophosphate intoxication?

open access: yesJ Lab Physicians, 2018
Kumar S   +3 more
europepmc   +1 more source

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