Results 291 to 300 of about 1,708,388 (381)

Distinct CTC Specific RNA Profile Enables NSCLC Early Detection and Dynamic Monitoring of Advanced NSCLC

Advanced Science, EarlyView.
A quantitative CTC RNA assay is developed by incorporating multi‐antibody‐based CTC isolation and specific mRNA quantification using RT‐ddPCR. The NSCLC CTC ScoreD demonstrates high accuracy for early‐stage NSCLC detection, significantly outperforming serum CEA. NSCLC CTC ScoreM exhibits a more accurate early‐warning of responses to different therapies
Xiaoyu Wang, Pi Ding, Wenjuan Xu, Lei Qiu, Jing Ren, Yucheng Fei, Zhili Wang, Cheng Li, Yufei Xing, Mingjing Shen, Yawen Zhu, Yun Guo, Na Sun, Renjun Pei, Minhua Shi   +14 more
wiley   +1 more source

Falsely Increased hCG in Patients with High Leukocyte Counts [PDF]

, 2013
Marion L. Snyder, Carmen Wiley, Ross J. Molinaro, James Ritchie, Corinne R. Fantz   +4 more
openalex   +1 more source

A Bio‐Adaptive Janus‐Adhesive Dressing with Dynamic Lubrication Overlayer for Prevention of Postoperative Infection and Adhesion

Advanced Science, EarlyView.
Slippery‐adhesive Janus gel dressing exhibits both stable tissue adhesive and outstanding efficiency in repelling physiological fluids. As a physical barrier, a liquid‐infused surface with a dynamic lubrication overlayer possesses excellent antibiofouling properties, making it highly effective in preventing bacterial infections and postoperative tissue
Yuan Gao, Junchang Guo, Shuangyang Li, Liansong Ye, Binyang Lu, Jiaxin Liu, Jing Luo, Yijia Zhu, Liuxiang Chen, Tingfa Peng, Jinlong Yang, Dehui Wang, Chaoming Xie, Xu Deng, Bing Hu   +14 more
wiley   +1 more source

STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

Advanced Science, EarlyView.
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken, Christophe Deben, Evelien Smits, Jonas R.M. Van Audenaerde   +3 more
wiley   +1 more source

Effect of gamma-irradiation on the differential leukocyte count in fish Poecilia reticulata [PDF]

, 2014
A. Renčko, Silvia Ondrašovičová, Drahomíra Sopková, Jana Ondrašovičová   +3 more
openalex   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction

Advanced Science, EarlyView.
Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang, Yuan Fang, Xiaoming Qin, Yiwei Zhang, Bo Kang, Li Zhong, Baoxin Liu, Jiachen Luo, Yidong Wei   +8 more
wiley   +1 more source

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

Advanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng, Yansong Wang, Haoyue Huang, Yinglong Ding, Jun Wang, Meili Liu, Kun Song, Lianbo Shao, You Yu, Ziying Yang, Zhenya Shen   +10 more
wiley   +1 more source

Polyaspartic Acid‐Calcium‐Lanthanum Complexes Induce Antibacterial Remineralization of Dentin and In‐Depth Occlusion of Dentinal Tubules

Advanced Science, EarlyView.
Polyaspartic acid‐calcium‐lanthanum (PAsp‐Ca‐La) complexes could induce antibacterial remineralization of demineralized dentin and in‐depth occlusion of dentinal tubules (DTs) with lanthanum‐doped hydroxyapatite (La‐HAp) via polyelectrolyte‐cation complexes pre‐precursor (PCCP) process, allowing the release of La3+ in response to acids generated by ...
Ling Zhu, Wei Liu, Yizhou Zhang, Zhifang Wu, Yiru Wang, Yuedan Xu, Haiyan Zheng, Hongli Zhang, Mengfei Yu, Xiaoting Jin, Zhe Wang, Zihuai Zhou, Baiping Fu   +12 more
wiley   +1 more source

Highly Absorbent Ultrafast Self‐Gelling Starch Microparticles for Robust Wet‐Tissue Adhesion and Instant Hemostasis

Advanced Science, EarlyView.
The aldehyde‐ and catechol‐modified starch (ACS) microparticle (MP) is developed by chemical modifications and freeze‐milling after calcium intercalation for highly absorbent and tissue‐adhesive properties. The ACS‐MP can be self‐gelled upon contact with biological fluids and blood on tissue surfaces, rapidly absorbing them and achieving robust wet ...
Soohwan An, Jihoon Jeon, Seung Yeop Han, Mi Jeong Lee, Tae‐Gyeong Oh, Eun Je Jeon, Dong Jin Joo, Seung‐Woo Cho   +7 more
wiley   +1 more source