Results 81 to 90 of about 765,746 (286)

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Age and leukocyte count as prognostic factors on acute lymphoblastic leukemia: hgmlal07 cohort

Duazary, 2016
In order to establish the cutoff with prognostic implications for white blood cell count and age at diagnosis in adults with acute lymphoblastic leukemia (ALL), we conducted an observational, descriptive and analytical study nested in a retrospective ...
Washington Ladines-Castro, Adrián Santoyo-Sánchez, Etta Rozen-Fuller, Irma Olarte-Carrillo, Adolfo Martínez-Tovar, Humberto Castellanos-Sinco, Juan Collazo-Jaloma, Christian Omar Ramos-Peñafiel   +7 more
doaj   +1 more source

Platelet count in men with a habit of alcohol drinking

Platelets, 2020
Alcohol inhibits platelet function, and platelet count is often reduced in individuals with alcohol use disorder. However, the relation of habitual alcohol drinking with platelet count in a general population remains to be determined.
Ichiro Wakabayashi
doaj   +1 more source

Impact of Six‐Month Monitoring Compared to Three‐Month Monitoring of Laboratories During Methotrexate Therapy

Arthritis Care &Research, EarlyView.
Objective To evaluate whether extending the American College of Rheumatology–recommended monitoring interval for complete blood count and liver function tests in patients receiving methotrexate (MTX) affects timely detection of medication‐related toxicity.
Spencer Simko, Ray Zhang, Sohini Mukherjee, Puneet Bajaj, Bonnie L. Bermas   +4 more
wiley   +1 more source

Mathematical predictive relationship of CD4+ lymphocytes and total leukocytes in HIV-infected patients

HIV & AIDS Review. International Journal of HIV-Related Problems
Introduction Different parameters have been established to direct the treatment of patients with human immunodeficiency virus (HIV) infection, such as CD4+ lymphocyte values, and it is of clinical interest to have methodologies that accurately predict ...
Signed Esperanza Prieto Bohorquez, Joao Cuesta, César Alejandro Valdés Cadena, Carlos Eduardo Pérez Díaz, Sandra Medina Araujo, Ribká Soracipa Muñoz, Andrés David Ibarra, Eduardo Méndez Pino, Sandra Catalina Correa Herrera, Javier Oswaldo Rodríguez Velasquez   +9 more
doaj   +1 more source

Leukocyte Count and Coronary Artery Disease Events in People with HIV: A Longitudinal Study.

, 2023
BACKGROUND People with HIV (PWH) have increased cardiovascular risk. Higher leukocyte count has been associated with coronary artery disease (CAD) events in the general population. It is unknown whether the leukocyte-CAD association also applies to PWH.
Kootstra, Neeltje A, Kouyos, Roger D, Günthard, Huldrych F, Reiss, Peter, Marzolini, Catia, Buvelot, Hélène, Fellay, Jacques, Thurnheer Zürcher, Maria Christine, Seneghini, Marco, Tarr, Philip E, Ryom, Lene, Thorball, Christian W, Ledergerber, Bruno, Schöpf, Isabella Christina, Avery, Emma F, Bernasconi, Enos, Cavassini, Matthias, Kleynhans, Julia N, Braun, Dominique L   +18 more
core   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Elevated leukocyte count as a harbinger of systemic inflammation, disease progression, and poor prognosis: a review [PDF]

, 2018
Total leukocyte count increases significantly in response to infection, trauma, inflammation, and certain diseases. Factors affecting leukocyte count in healthy adults include sex, hormonal milieu, genetic inheritance, stress level, diet, nutrition, and ...
Strzelec, B.; Division of Anatomy, Department of Human Morphology and Embryology, Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland, Chmielewski, P.P.; Division of Anatomy, Department of Human Morphology and Embryology, Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland   +1 more
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Optimal dosing based on leukocyte count and MCV as target.

, 2014
A. Evolution of leukocyte count in response to optimum 6-MP dosing. B. Evolution of ΔMCV response with optimum 6-MP dose. Dashed lines represent critical leukocyte and target MCV levels and solid dots represent clinical data for an average patient.
Ann E. Rundell (196053), Robert E. Hannemann (643680), Doraiswami Ramkrishna (207971), Devaraj Jayachandran (643679), Terry A. Vik (643681)   +4 more
core   +1 more source