Orbital Complications of Acute Rhinosinusitis in Adulthood: Predictors of Outcome and Management
In a multicenter cohort of 213 adults with orbital complications of acute rhinosinusitis, 68% required surgery and the modified Chandler classification was the strongest predictor of treatment modality. While abscess‐related and type II complications frequently necessitated surgical management, final ophthalmologic outcomes were uniformly favorable ...
Alessandro Vinciguerra +41 more
wiley +1 more source
Case Report: Co-existence of <i>BCR::PDGFRA</i> gene fusion and <i>PDGFRA</i> variants in myeloid neoplasm with persistent leukocytosis, large splenomegaly, and eosinophilia. [PDF]
Xiao Z +10 more
europepmc +1 more source
Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang +6 more
wiley +1 more source
Case Report: Chronic myeloid leukemia in a 13-year-old-a rare pediatric case of extreme hyperleukocytosis in chronic phase. [PDF]
Asees M, Abdalhaq T, Amer J.
europepmc +1 more source
ABSTRACT Limb salvage using free tissue transfer in patients with rare autoinflammatory syndromes is poorly described, and the safety of microvascular reconstruction in this population remains uncertain. Hereditary pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome is characterized by dysregulated inflammation, pathergy, and impaired ...
Michael M. Talanker +9 more
wiley +1 more source
A 69-year-old man with acute generalized exanthematous pustulosis. [PDF]
Ruan Y, Chen M, Zhao X.
europepmc +1 more source
Chorioamnionitis treatment for women with isolated intrapartum fever: A cost‐effectiveness analysis
Abstract Objective Intrapartum fever (≥38°C) occurs in many laboring patients annually in the United States, but whether an isolated fever should be treated as chorioamnionitis remains controversial. Antibiotic treatment may help reduce the impact of infection as compared to expectant management but may lead to other complications and increase costs ...
Prakrunya Subhasree Badrinarayan +2 more
wiley +1 more source
Integrating Modified National Early Warning Score 2, computed tomography staging, and laboratory markers for enhanced prognostic stratification in emphysematous pyelonephritis. [PDF]
Sevik C, Erbin A, Canat HL.
europepmc +1 more source
Leukocytosis: The mysteries within [PDF]
Javier, Munoz, Yue, Guo
openaire +2 more sources
Clinical and computed tomography findings of fatal poxviral vasculitis in a domestic shorthair cat
Abstract This report describes the clinical presentation, haematological abnormalities and imaging findings of systemic poxvirus infection in a cat that resulted in widespread severe dermal oedema and systemic inflammatory response syndrome. The cat lacked cutaneous lesions before the onset of dermal oedema, but developed crusting skin lesions and a ...
Mica Taylor +5 more
wiley +1 more source

