Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
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Beyond the Tropics: Clinical Presentation and Epidemiology of Travel-Associated Dengue Fever in a Non-Endemic European Setting. [PDF]
Dollensky L +5 more
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Endobronchial Aspergillosis Presenting as an Isolated Airway Lesion in an Immunocompromised Patient
Endobronchial Aspergillus infection should be considered in immunocompromised patients presenting with airway obstruction, even in the absence of parenchymal lung involvement. This case highlights the potential for rapid clinical deterioration and the diagnostic challenges in distinguishing endobronchial aspergillosis from more aggressive forms of ...
Mohsen Sadeghi +3 more
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Divergence between initial and cumulative manifestations in systemic lupus erythematosus: effect of age and sex in a prospective lupus cohort from Pakistan. [PDF]
Khan A +6 more
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ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter +20 more
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Efficacy and safety comparison of hetrombopag and eltrombopag in children with cancer therapy-induced thrombocytopenia: a single-center retrospective study. [PDF]
Yu LT +8 more
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Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy
The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins +6 more
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Safety profile of chimeric antigen receptor T-cell therapy in relapsed/refractory multiple myeloma: A systematic review and meta-analysis of proportions from clinical trials. [PDF]
Filippatos C +7 more
europepmc +1 more source
Summary Childhood autoimmune neutropenia (AIN) encompasses heterogeneous entities; phenotype‐specific immunological profiles and their relationship to infection outcomes remain incompletely defined. To characterise clinical, immunological and long‐term outcomes across distinct phenotypes of childhood AIN.
Ioanna Saougou +5 more
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Efficacy and safety of thymosin combined with anticancer therapy for esophageal cancer: a systematic review and meta-analysis of randomized controlled trials. [PDF]
Sun T +5 more
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