Results 11 to 20 of about 9,864 (178)
Topical Imiquimod for Oral Cavity Leukoplakia and Dysplasia: A Scoping Review. [PDF]
Otolaryngol Head Neck SurgAbstract Objective Imiquimod, a toll‐like receptor 7 agonist, is currently FDA‐approved for treatment of actinic keratoses, superficial BCC, and external genital warts. It has also demonstrated promise in off‐label use in the treatment of oral cavity leukoplakia and dysplasia.
Scharner MK +3 more
europepmc +2 more sources
PLoS ONE, 2021 Tobacco smoking is associated with an increased risk of oral leukoplakia and head and neck cancer. Although it has recently been reported that the establishment of an immunosuppressive microenvironment in oral potentially malignant disorders may lead to ...
Takahiro Yagyuu +3 more
doaj +1 more source
Critical Reviews in Oral Biology & Medicine, 1995 Leukoplakia has evolved as a clinico-pathologic concept over many years, with the current clinical designation being accepted worldwide. Reflective of the biology of leukoplakia is the concept of cellular atypia and epithelial dysplasia. Adding to a better understanding of leukoplakia in general has been the definition of relevant clinical subsets ...
openaire +2 more sources
Journal of Orofacial Sciences, 2023 Introduction: Chemerin is a multifunctional chemoattractant cytokine, encoded by RARRES2 gene. Its role in oral carcinogenesis is largely unexplored. Study was undertaken to evaluate the role of salivary chemerin as a potential biomarker in the early ...
Karthika Pradeep Susha, Rathy Ravindran
doaj +1 more source
Oral Leukoplakia – Is Biopsy at the Initial Appointment a Must? [PDF]
Journal of Clinical and Diagnostic Research, 2014 Background: Oral leukoplakia is a potentially malignant disorder of the oral cavity. Leukoplakias with chances of undergoing malignant transformation owing to the presence of dysplastic changes may not be clinically distinguishable from leukoplakias ...
Sunil Mutalik +4 more
doaj +1 more source
Clinical periodontal diagnosis
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source
Immunohistochemical Evaluation of EGFR Expression in Oral Dysplastic and Non-Dysplastic Leukoplakia [PDF]
Journal of Mashhad Dental School, 2023 Background: This study aimed to evaluate the expression of epidermal growth factor receptor (EGFR) in oral leukoplakia with and without dysplasia and normal mucosa by immunohistochemistry.Materials and Methods: In this study, 45 samples of oral ...
Nasrollah Saghravanian +3 more
doaj +1 more source
Chemoprevention in oral leukoplakia: challenges and current landscape
Frontiers in Oral Health, 2023 Oral potentially malignant disorders have the potential to transform into oral cancer. Oral leukoplakia is a prevalent OPMD with a 9.8% malignant transformation rate.
Victor de Mello Palma +5 more
doaj +1 more source
Immunoexpression of Podoplanin in Leukoplakia and Oral Squamous Cell Carcinoma and its Correlation with Survival: A Research Protocol [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Podoplanin (PDPN) is a well-conserved mucin-type transmembrane glycoprotein. According to various studies, podoplanin expression is seen in various human cancers and it also encourages the progression of the tumour.
Samiha Jameel Ahmed Khan +4 more
doaj +1 more source
Research progress of oral hairy leukoplakia [PDF]
Kouqiang yixueOral hairy leukoplakia is an oral mucosal disease caused by Epstein-Barr virusinfection of oral squamous epithelial cells. Oral hairy leukoplakia presents as a non-removable, corrugated and wrinkled white plaque sometimes with hair-like projections ...
MO Longhui, LIANG Jing, WANG Jiongke, LIU Tiannan, ZENG Xin
doaj +1 more source