Results 101 to 110 of about 29,263 (276)
ABSTRACT Background Histological grading of oral epithelial dysplasia (OED) is used for predicting malignant transformation risk. However, grading is associated with significant subjectivity and observer variability leading to inconsistency in prognosis prediction.
Hanya Mahmood +10 more
wiley +1 more source
The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]
A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé +14 more
core +1 more source
What's new? Oral cancer burden is high in India. Risk stratification for selection of high‐risk individuals could enable early detection through efficient screening programs. We conducted a cross‐sectional screening study in Northeast India to develop and validate an oral precancer/cancer risk prediction model.
Kunal Oswal +17 more
wiley +1 more source
Malignant Transformation of Buccal Mucosa Leukoplakia in a Patient With Dyskeratosis Congenita [PDF]
Nobuhide Ohashi +4 more
openalex +1 more source
(1) TREM2+ TAMs promote CD8+ T cell exhaustion by upregulating BHLHE40 through the SPP1–CD44 axis, contributing to a suppressive tumour immune microenvironment in HNSCC. (2) CD8+ Tex induced by TREM2+ TAMs facilitates immune escape and promotes tumour cell metastasis via the lymphangion.
Zhuokai Wu +11 more
wiley +1 more source
RNA Analysis Uncovers Pathogenic PARN Variant in Dyskeratosis Congenita
Using WGS and RNA analysis, we identified a branch point‐disrupting variant in the PARN gene and elucidated its pathogenic molecular mechanism in a child with atypical dyskeratosis congenita presentation. ABSTRACT Dyskeratosis congenita (DC) is a rare genetic disorder caused by impaired telomere maintenance, leading to diverse clinical manifestations ...
Daria Akimova +3 more
wiley +1 more source
Avascular Necrosis and Minimal Trauma Fractures in Telomere Biology Disorders
Avascular Necrosis (AVN) and Minimal Trauma Fractures (MTF) cause significant morbidity in people with Telomere Biology Disorders (TBDs). They occur more frequently in young patients and in those with autosomal recessive (AR) or X‐linked recessive (XLR) than in autosomal dominant (AD) genotypes.
Arman M. Niknafs +3 more
wiley +1 more source
Clinical presentations of viral and parasitic diseases in HIV infection [PDF]
Представлений аналіз залежності клінічних проявів інфекцій вірусної і паразитарної етіології на тлі ВІЛ-інфекції від рівня CD4-лімфоцитів. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/26618Представлен ...
Magufwa, Alex +5 more
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