Results 71 to 80 of about 12,052 (197)

Circulating Mitochondrial DNA Measures Across Malignancies: Diagnostic Accuracy and Prognostic Associations

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Circulating mitochondrial DNA is being investigated as a liquid‐biopsy biomarker because of its high copy number and release during cellular stress. However, diagnostic estimates vary across tumor types and assays, and prognostic studies have measured both cell‐free mtDNA and cellular blood‐derived mtDNA, which are not analytically ...
Ziying Zhang   +5 more
wiley   +1 more source

Oral Carcinoma Cuniculatum: Diagnostic Challenges and Emerging Perspectives—Case Report

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Oral carcinoma cuniculatum (OCC) is a rare subtype of squamous cell carcinoma (SCC). It is characterized by a locally aggressive, burrowing lesion associated with an osteolytic defect yet lacks obvious cytological atypia. Although OCC has been described in the literature, its rarity, clinical unfamiliarity, and distinct burrowing ...
Toniya Raut   +6 more
wiley   +1 more source

The Microbiome of Potentially Malignant Oral Leukoplakia Exhibits Enrichment for Fusobacterium, Leptotrichia, Campylobacter, and Rothia Species

open access: yesFrontiers in Microbiology, 2017
Oral leukoplakia presents as a white patch on the oral mucosa and is recognized as having significant malignant potential. Although colonization of these patches with Candida albicans is common, little is known about the bacterial microbiota of these ...
Abdrazak Amer   +3 more
doaj   +1 more source

Identification of Prognostic Genes Relevant With the Nuclear Factors of Activated T Cells Based on Transcriptomics in Oral Squamous Cell Carcinoma

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Background It has previously been demonstrated that the nuclear factor of activated T cells (NFAT) is crucial for the development of tumors. Given OSCC's drug resistance and poor outcomes, identifying NFAT‐associated prognostic genes is urgent for better treatment.
Julaiti Tuerxun   +2 more
wiley   +1 more source

Automated Differentiation of Oral Red‐White Lesions: An Interpretable Deep Learning Approach Combining Ensemble Architectures and Saliency Maps

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Introduction Oral Potentially Malignant Disorders (OPMDs), including Leukoplakia and Erythroplakia, carry significant risks of malignant transformation. Early differentiation from confounding inflammatory conditions like Oral Lichen Planus (OLP) and Candidiasis is critical yet challenging due to visual similarities.
Mahsa Koochaki   +5 more
wiley   +1 more source

Malignant Transformation of Oral Epithelial Dysplasia in Southern Finland

open access: yesHead &Neck, Volume 48, Issue 8, Page 2231-2237, August 2026.
ABSTRACT Background Oral epithelial dysplasia (OED) often precedes oral squamous cell carcinoma (OSCC). The aim was to elucidate the risk and time of malignant transformation (MT) of OED. Methods Patients diagnosed with OED between 2001 and 2011 in Helsinki and Uusimaa, Finland were included.
Katariina Leino   +3 more
wiley   +1 more source

Atypical Whitish Gingival Plaque

open access: yes
Oral Diseases, EarlyView.
Maria Eduarda Camilo Rezende   +3 more
wiley   +1 more source

N‐Terminal Variant p.Ala2Val in X‐Linked Dyskeratosis Congenita Gene (DKC1) Disrupts Its Post‐Translational Modification and Nucleolar Localization

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 8, August 2026.
Major symptoms of dyskeratosis congenita. Predicted nuclear localization site at N‐terminus of DKC1 protein. Comparison of nuclear localization for DKC1 showing normal localization for wild‐type versus disruption of localization for p.Ala2Val. ABSTRACT Background Dyskeratosis congenita (DKC) is typically characterized by the triad of abnormal cutaneous
Taimoor I. Sheikh, John B. Vincent
wiley   +1 more source

Deciphering the Relationship Between Alcohol Consumption, Oropharyngeal Cancers, and Socioeconomic Determinants

open access: yesAlcohol, Clinical and Experimental Research, Volume 50, Issue 8, August 2026.
Using Mendelian randomization, we show that alcohol intake frequency increases oropharyngeal cancer risk independently of socioeconomic status, while the apparent protective effect of drinking with meals is explained by higher household income. Drinks per week independently increase stomatitis risk.
Tareq Al‐Ahdal   +3 more
wiley   +1 more source

A quantitative expression of Ki-67 to evaluate malignant transformation rate in potentially malignant disorders

open access: yesJournal of Dr. NTR University of Health Sciences, 2018
Objective: To evaluate the quantitative expression of Ki-67 in oral leukoplakia, oral submucous fibrosis (OSF) and to compare their expression with normal oral epithelium.
Mani D Chitipothu   +5 more
doaj   +1 more source

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