Results 151 to 160 of about 271,704 (310)
Assessment of accident rate at lithuanian railways level crossings
Purpose. The most pressing problem facing the rail traffic safety experts is an accident rate at the railway level crossings. The purpose is to investigate the circumstances, which affect traffic safety at the level crossings, and to offer effective ...
Lionginas Liudvinavichius +1 more
doaj
Crossings in clustered level graphs.
Cluster-Graphen sind ein erweitertes Graph-Modell mit einem rekursiven Clustering der Knoten entsprechend einer gegebenen Inklusionsrelation. Diese bedeutende Technik um Zusammengehörigkeit bestimmter Teile des Graphen auszudrücken wird in vielen Anwendungen benutzt, etwa biochemischen Reaktionsnetzen oder UML Klassendiagrammen.
openaire +2 more sources
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Old low level road crossing of Adelaide River [PDF]
Old low level road crossing of Adelaide River from new high level Verburg Bridge ...
core
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Nuclear spin-hyperpolarization generated in a flavoprotein under illumination: experimental field-dependence and theoretical level crossing analysis. [PDF]
Ding Y +10 more
europepmc +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The energy-level crossing behavior and quantum Fisher information in a quantum well with spin-orbit coupling. [PDF]
Wang ZH, Zheng Q, Wang X, Li Y.
europepmc +1 more source

