Results 241 to 250 of about 14,055,750 (308)

Improved interfacial-bonding strength and electronic structure properties of graphene-reinforced Al composites by Cu coating. [PDF]

RSC Adv
Jon SH, Ri JB, Jong C, Jong UG, Hong S.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Abetalipoproteinemia With a Novel Microsomal Triglyceride Transfer Protein Gene Mutation and Unique Oxidized Lipoprotein Levels. [PDF]

J Med Cases
Hamasaki M, Hara K, Kotani K.
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

MIRA-EDCA: Multi-Indicator Responsive Adaptation of the Contention Window for Priority-Aware Safety Broadcasting in IEEE 802.11p Vehicular Networks. [PDF]

Sensors (Basel)
Lazarev A, Sadiq M, Tang H, Shakhobiddinov A, Zhang A, Sadatdiynov K, Reypnazarov E, Akhmedov N.   +7 more
europepmc   +1 more source

Distinct gradients of cortical architecture capture visual representations and behavior across the lifespan. [PDF]

Elife
Chen X, Liu X, Hoyos PM, Daniel Hertz E, Yao JK, Zhen Z, Gomez J.   +6 more
europepmc   +1 more source

A Divide-and-Conquer Embedded Correlated Wavefunction Transfer Learning Approach for Chemically Accurate Condensed-Phase Interatomic Potentials: Liquid Water as a Test Case. [PDF]

J Phys Chem Lett
Bian X, Carter EA.
europepmc   +1 more source