Results 61 to 70 of about 13,064,947 (308)

Two-Level Parallelization Surface Mesh Generation for Complex Assembly Models [PDF]

open access: yesJisuanji gongcheng
With the goal of fulfilling the demand for large-scale numerical simulations in practical engineering applications, a two-level parallel surface mesh generation method suitable for a high-performance computer distributed shared storage system is proposed
XU Quan, LENG Juelin, LIU Tiantian, ZHENG Peng
doaj   +1 more source

Generative Language Models for Paragraph-Level Question Generation

open access: yesProceedings of the 2022 Conference on Empirical Methods in Natural Language Processing, 2022
Powerful generative models have led to recent progress in question generation (QG). However, it is difficult to measure advances in QG research since there are no standardized resources that allow a uniform comparison among approaches. In this paper, we introduce QG-Bench, a multilingual and multidomain benchmark for QG that unifies existing question ...
Asahi Ushio   +2 more
openaire   +4 more sources

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gigawatt level, 10 fs high efficiency visible pulse generation

open access: yesAPL Photonics
We present a robust approach capable of generating ultrashort pulses in the visible (VIS) spectral range through second-harmonic generation of broadened pulses centered at around 1030 nm.
Pedram Abdolghader   +9 more
doaj   +1 more source

Design and analysis of 15-level inverter with a new voltage level generation method

open access: yesAin Shams Engineering Journal
Multilevel inverters (MLIs) are commonly used in high-power applications for their ability to reduce Total Harmonic Distortion (THD) and improve power quality. However, the need for multiple DC sources in MLIs can increase complexity and cost. This study
Hasan Hataş
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Seven‐level dual‐buck inverter for photovoltaic power generation

open access: yesIET Renewable Power Generation
A power processing system (PPS) with a seven‐level dual‐buck inverter (SLDBI) for a photovoltaic (PV) power generation system is proposed. The PPS is comprised of a boost power converter and an SLDBI.
Jinn‐Chang Wu   +3 more
doaj   +1 more source

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