Results 161 to 170 of about 800,570 (313)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Thirty years of glacier grounding line retreat in Antarctica. [PDF]

Proc Natl Acad Sci U S A
Rignot E, Scheuchl B, Barre JB, Brancato V, Charrier L, Chen H, Ciraci E, Dinh A, Herreid S, Jeong S, Li X, Mitchell T, Mohajerani Y, Shamsian S, Tolpekin V, Velicogna I, Wollersheim M.   +16 more
europepmc   +1 more source

Effect of Foot Orthoses on Midfoot Pain and the Volume of Bone Marrow Lesions in the Midfoot: A Randomized Mechanism of Action Study

Arthritis Care &Research, EarlyView.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

Separating tectonic and climate signals in Holocene sea-level records using marine terraces in central Chile. [PDF]

Sci Rep
Melnick D, Jara-Muñoz J, Garrett E, Plissart G, Freisleben R, Strecker MR.   +5 more
europepmc   +1 more source

The Calculation Method of Ice Resistance in Level Ice by the Ice-Covered Hull Model

Journal of the Japan Society of Naval Architects and Ocean Engineers, 2021
Keisuke Anzai, Yutaka Yamauchi, Shigeya Mizuno   +2 more
openaire   +2 more sources

Near-field sea-level variability in northwest Europe and ice sheet stability during the last interglacial

, 2015
Antony J. Long, Natasha Barlow, Freek S. Busschers, K.M. Cohen, W. Roland Gehrels, Leanne Wake   +5 more
openalex   +2 more sources

What Do Large Language Models Know About Materials?

Advanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer, Thomas Wallmersperger, Gianaurelio Cuniberti   +2 more
wiley   +1 more source

Expertise shapes the kinematic and electromyographic characteristics of on-ice side-cutting in elite versus beginner ice hockey players. [PDF]

Sci Rep
Yu Z, Bi G, Qin Y, Wang W, Song Z, Wu F.
europepmc   +1 more source

An Overlooked Term in Assessment of the Potential Sea-Level Rise from a Collapse of the West Antarctic Ice Sheet

, 2013
Diandong Ren, M. J. Lynch, Lance M. Leslie   +2 more
openalex   +2 more sources

Antarctic ice dynamics amplified by Northern Hemisphere sea-level forcing

, 2020
Natalya Gomez, Michael E Weber, Peter U. Clark, J. X. Mitrovica, Holly Kyeore Han   +4 more
openalex   +2 more sources