Results 41 to 50 of about 7,802,667 (305)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Postural stability after operative reconstruction of the AFTL in chronic ankle instability comparing three different surgical techniques

Open Medicine
Chronic lateral ankle instability is a relatively frequent consequence after acute ankle sprain. In case of unsuccessful conservative treatment, surgical therapy is recommended to prevent osteoarthritis of the ankle joint.
Goetz Juergen, Baier Clemens, Vitzethum Georg, Grifka Joachim, Maderbacher Guenther, Springorum Hans-Robert   +5 more
doaj   +1 more source

The exclusive \bar{B} --> \pi e^+ e^- and \bar{B} --> \rho e^+ e^- decays in the two Higgs doublet model with flavor changing neutral currents

, 1998
We calculate the leading logarithmic QCD corrections to the matrix element of the decay b --> d e^+ e^- in the two Higgs doublet model with tree level flavor changing currents (model III).
Ali A., Aliev T. M., Aliev T. M., Atwood D., Atwood D., Buras A. J., Colangelo P., Deshpande N. G., Du D. S., E. O. ILTAN, Greub C., Greub C., Jaus W., Krüger F., Krüger F., Melikhov D., O’Donnell P. J., Paver N., Vainshtein A. I.   +18 more
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Bounds on charged higgs boson in the 2HDM type III from Tevatron [PDF]

, 2002
We consider the Two Higgs Doublet Model (2HDM) of type III which leads to Flavour Changing Neutral Currents (FCNC) at tree level. In the framework of this model we can use an appropriate form of the Yukawa Lagrangian that makes the type II model limit of
A. Djouadi, A. Mendez, B. Abbot, C. Li, D. Atwood, D. Atwood, D. Atwood, D. Atwood, D. Atwood, D. Atwood, D. Chang, F. Abe, G. Cvetic, J-Alexis Rodriguez, M. Carena, M. Rozo, M. Sher, Marc Sher, R. Martinez, Rodolfo A. Diaz, Rodolfo A. Diaz, S. Glashow, S. Nie, T. Affolder, T.P. Cheng, V. Abazov, W.S. Hou   +26 more
core   +2 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Enumerations of vertices among all rooted ordered trees with levels and degrees

, 2017
In this paper we enumerate and give bijections for the following four sets of vertices among rooted ordered trees of a fixed size: (i) first-children of degree $k$ at level $\ell$, (ii) non-first-children of degree $k$ at level $\ell-1$, (iii) leaves ...
Eu, Sen-Peng, Seo, Seunghyun, Shin, Heesung   +2 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Image-guided versus landmark-guided suprascapular nerve block for shoulder pain in rotator cuff tears: a systematic review

JSES Reviews, Reports, and Techniques
: Background: Suprascapular nerve block (SSNB) is a recognized treatment for chronic shoulder pain, including pain from rotator cuff tears. While it is purported that image-guided SSNB improve injection accuracy over landmark-guided techniques, the ...
Andrew Kailin Zhou, MB, BChir, MA (Cantab), MRCS (Eng), Dave Osinachukwu Duru, BA Hons (Cantab), Saroop Nandra, iBSc, MBBS, MRCS (Eng), Andrew Metcalfe, MBChB, BMedSc, PhD, FRCS (Tr&Orth), Salma Chaudhury, MB, BChir, MA (Cantab), PhD (Oxon), FRCS (Orth)   +4 more
doaj   +1 more source

Phase i study of \u27dose-dense\u27 pemetrexed plus carboplatin/radiotherapy for locally advanced non-small cell lung carcinoma. [PDF]

, 2011
BACKGROUND: This phase I study investigates the feasibility of carboplatin plus dose-dense (q2-week) pemetrexed given concurrently with radiotherapy (XRT) for locally advanced and oligometastatic non-small cell lung cancer (NSCLC).
Axelrod, Rita, Curran, Walter J, Denittis, Albert, Gilman, Paul, Machtay, Mitchell, Meyer, Thomas, Shen, Xinglei, Treat, Joseph, Werner-Wasik, Maria   +8 more
core   +1 more source