Results 71 to 80 of about 1,831,254 (293)

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Beyond guesswork: how accurate are surgeons at determining the degree of glenoid bone loss in instability surgery?

open access: yesJSES International
Background: Accurate measurement of glenoid bone loss (GBL) is critical to preoperative planning in cases of recurrent shoulder instability. The concept of critical bone loss has been established with a value of GBL >13.5% being associated with higher ...
Caleb A. LaVigne, MD   +5 more
doaj  

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Calcaneal tuberosity avulsion fractures: A systematic review & meta-analysis of fixation methods

open access: yesFoot & Ankle Surgery: Techniques, Reports & Cases
Calcaneal tuberosity avulsion fractures, although uncommon, pose significant challenges due to their complexity and high rates of complications. This systematic review evaluates the effectiveness of various surgical fixation techniques for these ...
Karissa Badillo, DPM   +2 more
doaj  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Integrating domain-specific resources: Advancing AI for foot and ankle surgery

open access: yesFoot & Ankle Surgery: Techniques, Reports & Cases
Large language models like ChatGPT offer significant potential for applications in medicine, including patient education and clinical support. This study evaluates the performance of ChatGPT-4, ChatGPT-4 enhanced with retrieval-augmented generation (RAG),
Steven R. Cooperman, DPM, MBA, AACFAS   +1 more
doaj  

Implementation of a Multidisciplinary Preoperative Protocol for Geriatric Hip Fractures Improves Time to Surgery at a Level III Trauma Center. [PDF]

open access: yesGeriatr Orthop Surg Rehabil, 2023
Meyer JR   +5 more
europepmc   +1 more source

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