In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker+8 more
wiley +1 more source
Background: Accurate measurement of glenoid bone loss (GBL) is critical to preoperative planning in cases of recurrent shoulder instability. The concept of critical bone loss has been established with a value of GBL >13.5% being associated with higher ...
Caleb A. LaVigne, MD+5 more
doaj
Response to commentson : Evaluation of clinical profile and screening guidelines of retinopathy of prematurity in an urban level III neonatal intensive care unit. [PDF]
Sanghi G, Sawhney JS, Kaur S, Kumar N.
europepmc +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász+6 more
wiley +1 more source
Calcaneal tuberosity avulsion fractures: A systematic review & meta-analysis of fixation methods
Calcaneal tuberosity avulsion fractures, although uncommon, pose significant challenges due to their complexity and high rates of complications. This systematic review evaluates the effectiveness of various surgical fixation techniques for these ...
Karissa Badillo, DPM+2 more
doaj
Inhibition and facilitation of eating by electric shock: III. A further study of the role of strain and of shock level [PDF]
Graham M. Sterritt
openalex +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
Integrating domain-specific resources: Advancing AI for foot and ankle surgery
Large language models like ChatGPT offer significant potential for applications in medicine, including patient education and clinical support. This study evaluates the performance of ChatGPT-4, ChatGPT-4 enhanced with retrieval-augmented generation (RAG),
Steven R. Cooperman, DPM, MBA, AACFAS+1 more
doaj
Implementation of a Multidisciplinary Preoperative Protocol for Geriatric Hip Fractures Improves Time to Surgery at a Level III Trauma Center. [PDF]
Meyer JR+5 more
europepmc +1 more source
Response of Plants to Air Pollutants. III. A Relation between Ascorbic Acid Levels and Ozone Susceptibility of Light-Preconditioned Tobacco Plants [PDF]
H. A. Menser
openalex +1 more source