Results 91 to 100 of about 1,986,463 (267)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Moderators of an intervention on emotional and behavioural problems: household- and school-level parental education. [PDF]

open access: yesEur J Public Health, 2022
Horoz N   +7 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

STUDY REGARDING THE DEVELOPMENT OF MOTOR ABILITY- SPEED - THROUGH METHODS AND MEANS SPECIFIC TO ATHLETICS AT HIGH SCHOOL PUPILS

open access: yesSport şi Societate, 2017
The aim of this research is to determine the most efficient methods and means of action for speed development under all manifestation forms at high school pupils and determination of their biometric level.
FlorianBENEDEK, Elena RAŢĂ
doaj  

What determines the prevalence of unregistered marriages?

open access: yesRussian Journal of Education and Psychology
Background. Non-marital unions have become a widespread phenomenon in society, firmly associated with partnership instability, childlessness or low number of children, and with families receiving social subsidies for children due to an incomplete family ...
Tatiana N. Kochetkova
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The level of education is associated with an anxiety-depressive state among men and women - findings from France during the first quarter of the COVID-19 pandemic. [PDF]

open access: yesBMC Public Health, 2023
Joannès C   +8 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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