Results 111 to 120 of about 7,537,263 (293)

The Relationship Between Level of Education, Cognitive Function and Medication Adherence in Patients with Schizophrenia. [PDF]

Neuropsychiatr Dis Treat, 2023
Zhu X, Wen M, He Y, Feng J, Xu X, Liu J.
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Building and Maintaining Self-Efficacy Beliefs: A Study of Entry-Level Vocational Education and Training Teachers. [PDF]

Vocat Learn, 2023
Gagnon N, Dubeau A.
europepmc   +1 more source

The role of geographic mobility in reducing education-job mismatches in the Netherlands. [PDF]

In this paper we investigate the relationship between geographic mobility and education-job mismatch in the Netherlands. We focus on the role of geographic mobility in reducing the probability of graduates working (i) jobs below their education level ...
Corvers, Frank, Hensen, Maud M., Vries, M. Robert de   +2 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Education Attainment of the Working-Age Population of Moscow According to the Population Census

Здоровье мегаполиса
Background. As a separate constituent entity of the Russian Federation, Moscow is characterized by significant heterogeneity of the population and its determinants of health, largely due to socioeconomic factors, the most important of which is the ...
V. G. Semenova, A. E. Ivanova
doaj   +1 more source

Culture, Ethnicity, and Level of Education in Alzheimer's Disease. [PDF]

Neurotherapeutics, 2022
Rosselli M, Uribe IV, Ahne E, Shihadeh L.   +3 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Moderators of an intervention on emotional and behavioural problems: household- and school-level parental education. [PDF]

Eur J Public Health, 2022
Horoz N, Buil JM, Koot S, van Lenthe FJ, Houweling TAJ, Oude Groeniger J, Koot HM, van Lier PAC.   +7 more
europepmc   +1 more source

The Bologna Process and the reform of medical education [PDF]

, 2009
In 1988, the Magna Charta Universitatum was signed at a meeting of European University rectors on the occasion of the 900th Anniversary of the University of Bologna to mark their commitment to harmonising the European Higher Education sector ...
Vassallo, Josanne
core