This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Comorbidities, level of education, and alcohol consumption are predictive factors of undernutrition among adult outpatients living with diabetes: a case at Hawassa governmental hospitals in Ethiopia. [PDF]
Meseret AA, Wondimagegne ZT.
europepmc +1 more source
Verbal intelligence is a more robust cross-sectional measure of cognitive reserve than level of education in healthy older adults. [PDF]
Boyle R +8 more
europepmc +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Avoiding Cutaneous Melanoma Requires Proper Sun Protection and a Correspondingly High Level of Education: A Case Control Study. [PDF]
Altan Ferhatoglu Z, Tas F.
europepmc +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Does the family affluence scale reflect actual parental earned income, level of education and occupational status? A validation study using register data in Sweden. [PDF]
Corell M +4 more
europepmc +1 more source
General certificate of education advanced level and advanced supplementary qualifications : national survey report [PDF]
core
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source

