Results 61 to 70 of about 1,986,463 (267)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Determinants of Household Education Expenditures by Education Level: The Case of Turkey
, 2020 There is a cost of educational attainment, which is covered by households as well as the state. While government spending on education emphasizes public responsibility for the realization and support of the existing service, education expenditures by households emphasize benefiting from educational services.
DEMİROGLARI, Sercan +1 more
openaire +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Educational attainment and employment among immigrants with disabilities
Economic and Social ReportsPersons with disabilities face disadvantages in employment, and these have implications for their well-being. The gap in employment between persons with and without disabilities is a widely used measure of inequality.
Christoph Schimmele +4 more
doaj +1 more source
Mìžnarodnij Endokrinologìčnij Žurnal, 2017 Background. According to the meta-analysis of studies, patients with diabetes mellitus (DM) have worse memory performance, information processing speed, executive functions compared to patients without DM.
N.M. Zherdova
doaj +1 more source
Formation and diagnostics levels of educational abilities of students in physical education
Слобожанський науково-спортивний вісник, 2015 Purpose: specify and theoretical basis for the content of educational tasks methodical practice, as a means of diagnosing the level of formation and pedagogical skills of students. Material and Methods: the analysis of more than 20 references, 12 work programs in the discipline "Physical Education" HEI III–IV accreditation levels.
Marakushyn, Andriy +3 more
openaire +4 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Comprehension of Posted Highway Traffic Signs in Iraq
Tikrit Journal of Engineering Sciences, 2012 Level of posted highway traffic signs (HTSs) comprehension by drivers is used to investigate the effectiveness of the posted HTSs in Iraq. Twenty four HTSs, different characteristics of drivers, and survey with questions of short answer and multiple ...
Aodai Abdul-Illah Ismail
doaj