Results 61 to 70 of about 169,732,242 (309)
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Relation Between Quality of Transportation and Nano-Scale Air Pollution
This study has two parts as determining traffic LOS and nanoscale analyses on the filters which can collect nanoparticle materials sourced by exhaust waste.
Elif Cicek +6 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Factors affecting adoption of service -oriented architecture (SOA) at an enterprise level [PDF]
Includes bibliographical references (leaves 104-112).Service-oriented computing is an emerging IT innovation. Among its manifestations is service-oriented architecture (SOA), an approach to designing and implementing IT solutions.
MacLennan, Elizaveta
core +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Illinois Fire Service Institute - 2020 Light and Fight_3
Instructor Hianik teaching at Light and Fight at the Illinois Fire Service Institute's Champaign campus in 2020.Institute of Museum and Library Services Grant ARPML-250797-OMLS ...
Illinois Fire Service Institute
core
XSEDE Level 1 Service Provider Security Agreement v1.1
Submitted by Janet Brown (brown@psc.edu) on 2016-04-04T16:17:09Z No. of bitstreams: 1 XSEDE Level 1 Service Provider Security Agreement.pdf: 699862 bytes, checksum: 09614d0c1f255de5679cd17ef4f6be60 (MD5)Made available in DSpace on 2016-04-04T16:17:09Z ...
XSEDE Security Working Group
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
A brochure announcing a new correspondence course offered through the Cooperative Extension ...
Virginia Cooperative Extension Service
core
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source

