Results 211 to 220 of about 34,849,215 (311)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Level set methods for gradient-free optimization of metasurface arrays. [PDF]

Sci Rep
Saad-Falcon A, Howard C, Romberg J, Allen K.   +3 more
europepmc   +1 more source

Comparative Study and Limits of Different Level-Set Formulations for the Modeling of Anisotropic Grain Growth. [PDF]

Materials (Basel), 2021
Murgas B, Florez S, Bozzolo N, Fausty J, Bernacki M.   +4 more
europepmc   +1 more source

Weighted Level Set Evolution Based on Local Edge Features for Medical Image Segmentation

IEEE Transactions on Image Processing, 2017
Alaa Khadidos, Victor Sanchez, Chang-Tsun Li   +2 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Modeling and Simulation of Dynamic Recrystallization Microstructure Evolution for GCr15 Steel Using the Level Set Method. [PDF]

Materials (Basel)
Chen X, Liu M, Yang Y, Si Y, Zhou Z, Zhou X, Jung D.   +6 more
europepmc   +1 more source

Level-Set Modeling of Grain Growth in 316L Stainless Steel under Different Assumptions Regarding Grain Boundary Properties. [PDF]

Materials (Basel), 2022
Murgas B, Flipon B, Bozzolo N, Bernacki M.   +3 more
europepmc   +1 more source

A Parametric Level Set Method for Electrical Impedance Tomography

IEEE Transactions on Medical Imaging, 2018
Dong Liu, A. K. Khambampati, Jiangfeng Du   +2 more
semanticscholar   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Level set-based XFEM modelling of the multi-scale hygro-mechanical behaviour of oak wood using morphological input from μ CT. [PDF]

Comput Mech
Livani MA, Suiker ASJ, van Maris MPFHL, Bosco E.   +3 more
europepmc   +1 more source