Results 61 to 70 of about 6,988 (254)
Thoughts on the chimera method of simulation of three-dimensional viscous flow [PDF]
The chimera overset grid is reviewed and discussed relative to other procedures for simulating flow about complex configurations. It is argued that while more refinement of the technique is needed, current schemes are competitive to unstructured grid ...
Steger, Joseph L.
core +1 more source
Enabling Secure Database as a Service using Fully Homomorphic Encryption: Challenges and Opportunities [PDF]
, 2013 The database community, at least for the last decade, has been grappling with querying encrypted data, which would enable secure database as a service solutions.
Gunda, Manikanta +2 more
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Neighbour coverage: a dynamic probabilistic route discovery for mobile ad hoc networks [PDF]
, 2008 Blind flooding is extensively use in ad hoc routing protocols for on-demand route discovery, where a mobile node blindly rebroadcasts received route request (RREQ) packets until a route to a particular destination is established.
Abdulai, J. +3 more
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Implementing public health at the national level [PDF]
Journal of Epidemiology and Community Health, 2001 Major public health problems require major solutions. To be successful, solutions need to be delivered at a number of levels. The English white paper Saving lives: our healthier nation 1 stated “We want to see healthier people in a healthier country. People improving their own health supported by communities working through local organisations against ...
openaire +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Taking 'participatory' in participatory modelling seriously [PDF]
, 2009 Over the last three decades participatory research processes have informed much international development and conservation work in developing countries. Public participation is also a growing legislative requirement in natural resource and environmental ...
Alexandridis, K. +2 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source