Results 161 to 170 of about 1,224,288 (285)

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

Advanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi, Mohammad Mahdi Hosseini, Ahmadreza Argha, Roxana Zahedi, Nigel H. Lovell, Hamid Alinejad‐Rokny   +5 more
wiley   +1 more source

Learning to connect: feasibility, acceptability and experiences in the social domain intervention for eating disorders. [PDF]

J Eat Disord
Ryan A, Arthur S, Lieu L, Kallianpur R, Mahmood F, Noebel N, Sherman-Chung M, McAdams CJ.   +7 more
europepmc   +1 more source

Full Issue Winter 2017 Volume 12, Issue 1 [PDF]

, 2018

core   +1 more source

Comment on “De Novo Reconstruction of 3D Human Facial Images from DNA Sequence”

Advanced Science, EarlyView.
This comment examines AI‐driven DNA‐based facial reconstruction, focusing on the Difface model. While such technologies promise biomedical and forensic applications, they pose significant ethical, legal, and methodological challenges. We emphasize transparency, benchmarking, and rigorous validation to avoid misinterpretation and misuse.
Jennifer K. Wagner, Nina Claessens, Caitlin M. Maloney, Peter Claes   +3 more
wiley   +1 more source

Stakeholder communication and client understanding of viral load suppression in Blantyre, Malawi-What role did U = U play before the flip the script campaign? [PDF]

PLoS One
Berner-Rodoreda A, Chione B, Ngwira E, Dambe R, Phiri S, Bärnighausen T, Alhassan Y, Taegtmeyer M, Tembo P, Feldacker C, Kiruthu-Kamamia C, Neuhann F.   +11 more
europepmc   +1 more source

The framework for the national curriculum : a report by the expert panel for the national curriculum review [PDF]

, 2011
James, Mary, Oates, Tim, Pollard, Andrew, Wiliam, Dylan   +3 more
core  

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Empowering Older Persons through Creative Engagement: A Feasibility Study of 'The House of Evergreen Arts' among Chinese Community Members in Newcastle, England. [PDF]

J Cross Cult Gerontol
Evans L, Darling C, Lee P, Tsang LY, Luddington S, Lai FH.   +5 more
europepmc   +1 more source

Single‐Target Pairing System (StarPair) for Large‐Scale Interrogation of Cell–Cell Interactions

Advanced Science, EarlyView.
This work presents a single‐target pairing system, StarPair, enabling cell–cell interaction studies by target combination in droplets. StarPair offers superior pairing efficiencies over 95% and operation frequencies of 105 pairs per 9.5 h for two‐target pairing, allowing large‐scale interrogation of immune cell‐cancer cell interactions and precise ...
Tianjiao Mao, Lang Nan, Miao Xu, Kehao Zeng, Yuchao Wang, Ziyu Han, Ho Cheung Shum   +6 more
wiley   +1 more source

The Effectiveness of Art Therapy on Children and Adolescents with ASD: A Systematic Review of RCTs. [PDF]

Healthcare (Basel)
Wei S, Lai AHY, Ho HWH.
europepmc   +1 more source