Results 111 to 120 of about 55,379 (247)

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Levenberg–Marquardt method for solving systems of absolute value equations

Journal of Computational and Applied Mathematics, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Iqbal, Javed, Iqbal, Asif, Arif, Muhammad   +2 more
openaire   +2 more sources

A Cascaded Strategy With Embodied Artificial Intelligence: Forward Kinematics Solutions for CCRobot‐S

Journal of Field Robotics, EarlyView.
ABSTRACT This paper presents a novel cable‐climbing mechanism: the Collaborative Climbing Robot Squad (CCRobot‐S), a variant of Reconfigurable Cable‐Driven Parallel Robots (R‐CDPR), specifically designed for the inspection and maintenance of stay cables.
Zhenliang Zheng, Yongyuan Xu, Xuchun He, Tin Lun Lam, Ning Ding   +4 more
wiley   +1 more source

An implementation of the partitioned Levenberg-Marquardt algorithm for applications in computer vision

Semina: Ciências Exatas e Tecnológicas, 2009
At several applications of computer vision is necessary to estimate parameters for a specific model which best fits an experimental data set. For these cases, a minimization algorithm might be used and one of the most popular is the Levenberg ...
Tiago Polizer da Silva, Marcela Hitomi Koyama, Maria Bernadete de Morais França, José Alexandre de França   +3 more
doaj  

Engineered Gravel Trench Hyporheic Exchange to Create Cold‐Water Thermal Refuges

River Research and Applications, EarlyView.
ABSTRACT Warming rivers are driving a loss or fragmentation of cold‐water habitat and providing the impetus to develop proactive thermal management approaches to maintain suitable habitat in rivers. One innovative approach is through the creation of cold‐water thermal refuges during periods of thermal stress for aquatic species.
Kathryn A. Smith, Edmund A. Halfyard, Christa Kelleher, Barret L. Kurylyk   +3 more
wiley   +1 more source

Unravelling Electronic Structure and Molecular Vibrations of Proteins in Virus Using Novel Correlated Plasmon‐Enhanced Raman Spectroscopy With Machine Learning

Small, EarlyView.
A novel, non‐destructive, stable, direct technique, named correlated plasmon‐enhanced Raman spectroscopy (CP‐ERS), which is based on a newly‐developed highly oriented single crystalline gold quantum dots (HOSG‐QDs) chip, is developed to measure and quantify molecular vibrations and electronic structure of analytes.
Vashu Kamboj, Shermine Ho, Fakhriedzwan Idris, Donald Heng Rong Ting, Khadijah Bte Kamsari Sanuh, Sylvie Alonso, Eng Soon Tok, Andrivo Rusydi   +7 more
wiley   +1 more source

Empirical Physics‐Based Normal Behavior Modeling of Drive Train Temperatures With High‐Resolution Wind Turbine Operating Data

Wind Energy, EarlyView.
ABSTRACT The installed wind energy capacity increases every year. However, operation and maintenance costs still make up a considerable portion of the levelized costs of electricity. This costs can be greatly reduced by the application of suitable early fault detection methods. The supervisory control and data acquisition system of wind turbines is one
Timo Lichtenstein, Victor von Maltzahn, Karoline Pelka   +2 more
wiley   +1 more source

Design and Validation of Zeroing Neural Network With Active Noise Rejection Capability for Time‐Varying Problems Solving

CAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Recently, the zeroing neural network (ZNN) has demonstrated remarkable effectiveness in tackling time‐varying problems, delivering robust performance across both noise‐free and noisy environments. However, existing ZNN models are limited in their ability to actively suppress noise, which constrains their robustness and precision in solving ...
Yilin Shang, Wenbo Zhang, Dongsheng Guo, Shan Xue   +3 more
wiley   +1 more source

Surface Flashover in 50 Years: III. Extreme Environments and Industrial Challenges

High Voltage, EarlyView.
ABSTRACT Modern high‐voltage electrical equipment operates in complex environments where surface conditions are subjected to multifaceted influences from electric fields, thermal gradients, contaminants, irradiation and other extreme environmental factors.
Zhen Li, Heng Zhang, He Gao, Ji Liu, Yoshimichi Ohki, George Chen, Shengtao Li   +6 more
wiley   +1 more source

Framework for X‐ray mirror surface shape fitting

Journal of Synchrotron Radiation, EarlyView.
The closed‐form expressions for elliptic cylinders, hyperbolic cylinders, ellipsoids, hyperboloids, and diaboloids used for X‐ray mirror surface shapes are summarized. Additionally, a four‐layer framework to fit the measured surface shape data in slope or height for convenient X‐ray mirror surface characterization is proposed.For accurate ...
Lei Huang, Ruochen Xu, Tianyi Wang, Jumpei Yamada, Joseph Dvorak, Corey Austin, Albert Van Eeckhout, Josep Nicolàs Roman, Kenneth Goldberg, Mourad Idir   +9 more
wiley   +1 more source