Results 241 to 250 of about 37,295 (269)
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Pseudomalabsorption of Levothyroxine
JAMA: The Journal of the American Medical Association, 1991--The issue of patient compliance with pharmacological therapy vs malabsorption of medication was explored in the context of persistent hypothyroidism despite the administration of large doses of levothyroxine sodium.--Retrospective case series.--Referred care in two large tertiary care centers.--Four patients, seen within two decades, with clinical ...
Bruce D. Weintraub +3 more
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Pediatrics, 1985
To the Editor.— We read the recent report by Lehrner and Weir1 of acute levothyroxine ingestions with concern. Advocacy of an aggressive approach disregards their own cases as well as the medical literature,2-5 Which contains at least seven cases of acute excessive ingestion of levothyroxine (five of which were overlooked by the authors).
J D, White, T L, Litovitz
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To the Editor.— We read the recent report by Lehrner and Weir1 of acute levothyroxine ingestions with concern. Advocacy of an aggressive approach disregards their own cases as well as the medical literature,2-5 Which contains at least seven cases of acute excessive ingestion of levothyroxine (five of which were overlooked by the authors).
J D, White, T L, Litovitz
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Potency of Levothyroxine Products
JAMA: The Journal of the American Medical Association, 1984Recently, the company that manufactures the levothyroxine product that we use most often in our practice switched to high-pressure liquid chromotography (HPLC) to monitor their product. As a result, the brand name product now contains 100% of expected potency as determined in our laboratory by radioimmunoassay.
Sheldon S. Stoffer, Walter E. Szpunar
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Unusual Malabsorption of Levothyroxine
Thyroid, 2000We report a 50-year-old woman, with overt hypothyroidism undergoing thyrotropin (TSH)-stimulating hormone suppressive levothyroxine (LT4) treatment after subtotal thyroidectomy. At her first visit to our department, the laboratory results revealed a borderline low free thyroxine (FT4) level accompanied by a clearly elevated TSH level.
Peter Mikosch +6 more
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Replacement Doses of Levothyroxine
Annals of Internal Medicine, 1982Excerpt To the editor: We read with interest the article by Rosenbaum and Barzel on levothyroxine replacement doses for primary hypothyroidism (1).
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Delayed Intestinal Absorption of Levothyroxine
Thyroid, 1995We report four female patients with nodular goiter (in two of the four due to Hashimoto's thyroiditis) and one male patient with frank hypothyroidism due to Hashimoto's thyroiditis in whom TSH-suppressive or replacement L-T4 therapy failed to suppress or, respectively, normalize serum TSH.
BENVENGA, Salvatore +4 more
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Interaction Between Rifampin and Levothyroxine
Southern Medical Journal, 1999Rifampin is a potent inducer of hepatic enzymes and is well documented to cause many clinically significant drug interactions. Studies in normal volunteers have shown its ability to decrease circulating levels of thyroid hormone, while having no effect on thyroid-stimulating hormone (TSH).
John Norwood +2 more
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Acute overdose of levothyroxine in a dog
Journal of the American Veterinary Medical Association, 1992An overdose of up to 850 levothyroxine sodium tablets (0.2 mg) in a healthy 6-year-old 16.8-kg dog induced an episode of vomiting and hippus within 9 hours of ingestion. The dog was treated with activated charcoal and saline (magnesium sulfate) cathartic. Initially the serum concentration of thyroxine (T4) 4,900.9 nmol/L.
S R, Hansen, S P, Timmons, D C, Dorman
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Levothyroxine Poisoning – Symptoms and Clinical Outcome [PDF]
Basic & Clinical Pharmacology & Toxicology, 2015 AbstractLevothyroxine (LT), T4, poisoning is rarely associated with a severe outcome. However, cases with significant complications have been reported. The aim of this study was to identify factors associated with symptoms of poisoning including late‐onset symptoms.
Birgitte Nygaard +5 more
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Tablet Formulation of Levothyroxine Is Absorbed Less Well Than Powdered Levothyroxine
Thyroid, 2003The comparative bioavailability of oral doses of levothyroxine (LT(4)) formulation taken as tablets, after being crushed, or chewed before swallowing has not been well studied. Three patients with hypothyroidism who showed persistent elevation of serum thyrotropin (TSH) despite taking 200, 150, and 125 microg of LT(4) tablets per day are presented ...
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